CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034975
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Microtubule-associated protein 
Protein Synonyms/Alias
  
Gene Name
 Mapt 
Gene Synonyms/Alias
 rCG_32645 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
187PVPMPDLKNVRSKIGacetylation[1]
187PVPMPDLKNVRSKIGubiquitination[2]
213GKVQIINKKLDLSNVacetylation[1]
231CGSKDNIKHVPGGGSacetylation[1]
244GSVQIVYKPVDLSKVacetylation[1]
250YKPVDLSKVTSKCGSacetylation[1]
276QVEVKSEKLDFKDRVacetylation[1]
280KSEKLDFKDRVQSKIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Microtubule; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 374 AA 
Protein Sequence
MAEPRQEFDT MEDQAGDYTM LQDQEGDMDH GLKAEEAGIG DTPNMEDQAA GHVTQARVAG 60
VSKDRTGNDE KKAKGADGKT GAKIATPRGA ATPGQKGTSN ATRIPAKTTP SPKTPPGSGE 120
PPKSGERSGY SSPGSPGTPG SRSRTPSLPT PPTREPKKVA VVRTPPKSPS ASKSRLQTAP 180
VPMPDLKNVR SKIGSTENLK HQPGGGKVQI INKKLDLSNV QSKCGSKDNI KHVPGGGSVQ 240
IVYKPVDLSK VTSKCGSLGN IHHKPGGGQV EVKSEKLDFK DRVQSKIGSL DNITHVPGGG 300
NKKIETHKLT FRENAKAKTD HGAEIVYKSP VVSGDTSPRH LSNVSSTGSI DMVDSPQLAT 360
LADEVSASLA KQGL 374 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW. 
Interpro
 IPR027324; MAP2/MAP4/Tau.
 IPR001084; Tau/MAP_tubulin-bd_rpt.
 IPR002955; Tau_protein. 
Pfam
 PF00418; Tubulin-binding 
SMART
  
PROSITE
 PS00229; TAU_MAP_1
 PS51491; TAU_MAP_2 
PRINTS
 PR01261; TAUPROTEIN.