CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043518
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 SUMO-protein ligase PIAS1 
Protein Synonyms/Alias
  
Gene Name
 PIAS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MADSAELKQMVMSLRubiquitination[1, 2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MADSAELKQM VMSLRVSELQ VLLGYAGRNK HGRKHELLTK ALHLLKAGCS PAVQMKIKEL 60
YRRRFPQKIM TPADLSIPNV HSSPMPATLS PSTIPQLTYD GHPASSPLLP VSLLGPKHEL 120
ELPHLTSALH PVHPDIKLQK LPFYDLLDEL IKPTSLAEII 160 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0019789; F:SUMO ligase activity; IEA:InterPro. 
Interpro
 IPR027227; PIAS1.
 IPR023321; PINIT.
 IPR003034; SAP_dom. 
Pfam
  
SMART
 SM00513; SAP 
PROSITE
 PS51466; PINIT
 PS50800; SAP 
PRINTS