UniProt Accession

 Q3TJ56_MOUSE; Q3TJ56 

Genbank Protein ID

 AC068607; AC068608; AC068662; AC072048; AK167576 

Genbank Nucleotide ID

 BAE39639.1 

Protein Name

 Staphylococcal nuclease domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 Snd1 

Gene Synonyms/Alias

 AL033314 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
177	SHTIRDLKYTIENPR	acetylation	[1]
177	SHTIRDLKYTIENPR	ubiquitination	[2]
193	FVDSHHQKPVNAIIE	acetylation	[1, 3]
249	EPFAAEAKFFTESRL	ubiquitination	[2]
346	KDKQFVAKVMQVLNA	acetylation	[1]
389	NIQDKNKKLRPLYDI	ubiquitination	[2]
414	RKKLIGKKVNVTVDY	ubiquitination	[2]
491	ARAIKNGKGLHSKKE	acetylation	[3]
513	DISGDTQKAKQFLPF	ubiquitination	[2]
515	SGDTQKAKQFLPFLQ	acetylation	[1]
515	SGDTQKAKQFLPFLQ	ubiquitination	[2]
541	VFSGSRLKLYLPKET	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 608 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004518; F:nuclease activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 

Interpro

 IPR016071; Staphylococal_nuclease_OB-fold.
 IPR006021; Staphylococcal_nuclease.
 IPR002071; Thermonucl_AS. 

Pfam

 PF00565; SNase 

SMART

 SM00318; SNc 

PROSITE

 PS01284; TNASE_2
 PS50830; TNASE_3 

PRINTS