CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038631
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Cald1 
Protein Synonyms/Alias
  
Gene Name
 Cald1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
247EFMTHKLKQTENAFSacetylation[1, 2]
247EFMTHKLKQTENAFSsuccinylation[2]
247EFMTHKLKQTENAFSubiquitination[3]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG 60
QVTDQVEAHV QNSVPDEESK PASSNTQVEG DEEAALLERL ARREERRQKR LQEALERQKE 120
FDPTITDGSL SGPSRRMQND SAENETAEGE EKRESRSGRY EVEETEVVIK SYQKNSYQDA 180
EDKKKEEKEE EEQEKLKGGS LGENQIKDEK IKKDKEPKEE VKSFLDRKKG FTEVKAQNGE 240
FMTHKLKQTE NAFSPSRSGG RASGDKEAEG APQVEAGKRL EELRRRRGET ENEEFEKLKQ 300
KQQEAALELE ELKKKREERR KVLEEEEQRR KQEEADRKAR EEEEKRRLKE EIERRRAEAA 360
EKRQKMPEDG LSEDKKPFKC FTPKGSSLKI EERAEFLNKS VQKSGVRSTH QAAVVSKIDS 420
RLEQYTNAIE GTKASKPMKP AASDLPVPAE GVRNIKSMWE KGSVFSAPSA SGTPNKETAG 480
LKVGVSSRIN EWLTKSPDGN KSPAPKPSDL RPGDVSGKRN LWEKQSVDKV TSPTKV 536 
Gene Ontology
 GO:0030478; C:actin cap; IDA:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0003779; F:actin binding; TAS:MGI.
 GO:0006936; P:muscle contraction; IEA:InterPro.
 GO:0006940; P:regulation of smooth muscle contraction; TAS:MGI. 
Interpro
 IPR006017; Caldesmon.
 IPR006018; Caldesmon_LSP. 
Pfam
 PF02029; Caldesmon 
SMART
  
PROSITE
  
PRINTS
 PR01076; CALDESMON.