UniProt Accession

 ENO_DROME; P15007; A4UZY9; A5XD39; A5XD43; B9EQS7; C0PV73; Q8IPX8; Q8MT10; Q9VQ38 

Genbank Protein ID

 X17034; AE014134; AE014134; AE014134; AE014134; AE014134; AY118449; BT014924; BT058002; BT072929; DQ864190; DQ864191; DQ864192; DQ864193; DQ864194; DQ864195; DQ864196; DQ864197; DQ864198; DQ864199; DQ864200; DQ864201; DQ864202; DQ864203; DQ864204; DQ864205; DQ864206; DQ864207; DQ864208; DQ864209; DQ864210; DQ864211; DQ864212; DQ864213 

Genbank Nucleotide ID

 CAA34895.1; AAF51344.2; AAN10455.1; AAN10456.1; AAN10457.1; AAN10458.1; AAM48478.1; AAT47775.1; ACM16712.1; ACN86077.1; ABH06825.1; ABH06826.1; ABH06827.1; ABH06828.1; ABH06829.1; ABH06830.1; ABH06831.1; ABH06832.1; ABH06833.1; ABH06834.1; ABH06835.1; ABH06836.1; ABH06837.1; ABH06838.1; ABH06839.1; ABH06840.1; ABH06841.1; ABH06842.1; ABH06843.1; ABH06844.1; ABH06845.1; ABH06846.1; ABH06847.1; ABH06848.1 

Protein Name

 Enolase 

Protein Synonyms/Alias

 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase 

Gene Name

 Eno 

Gene Synonyms/Alias

 CG17654 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
300	LISDAIAKAGYTGKI	acetylation	[1]
494	AGVKFAGKSFRKPQ*	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

 REGION 438 441 Substrate binding (By similarity).
 ACT_SITE 277 277 Proton donor (By similarity).
 ACT_SITE 411 411 Proton acceptor (By similarity).
 METAL 312 312 Magnesium (By similarity).
 METAL 361 361 Magnesium (By similarity).
 METAL 386 386 Magnesium (By similarity).
 BINDING 225 225 Substrate (By similarity).
 BINDING 234 234 Substrate (By similarity).
 BINDING 361 361 Substrate (By similarity).
 BINDING 386 386 Substrate (By similarity).
 BINDING 462 462 Substrate (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Glycolysis; Lyase; Magnesium; Metal-binding; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 500 AA 

Protein Sequence

Gene Ontology

 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0004634; F:phosphopyruvate hydratase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 

Interpro

 IPR000941; Enolase.
 IPR020810; Enolase_C.
 IPR020809; Enolase_CS.
 IPR020811; Enolase_N. 

Pfam

 PF00113; Enolase_C
 PF03952; Enolase_N 

SMART

  

PROSITE

 PS00164; ENOLASE 

PRINTS

 PR00148; ENOLASE.