CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033911
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Dihydropyrimidinase-related protein 3 
Protein Synonyms/Alias
  
Gene Name
 Dpysl3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
47YVTKVMSKSAADLISacetylation[1]
82DGTHYWSKNWAKAAAubiquitination[2]
134TAQKAIGKDNFTAIPacetylation[3]
134TAQKAIGKDNFTAIPubiquitination[2]
157RMSVIWDKAVATGKMacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 216 AA 
Protein Sequence
MLEMGITGPE GHVLSRPEEL EAEAVFRAIT VASQTNCPLY VTKVMSKSAA DLISQARKKG 60
NVVFGEPITA SLGIDGTHYW SKNWAKAAAF VTSPPLSPDP TTPDYINSLL ASGDLQLSGS 120
AHCTFSTAQK AIGKDNFTAI PEGTNGVEER MSVIWDKAVA TGKMDENQFV AVTSTNAAKI 180
FNLYPRKGRI AVGSDSDLVI WDPDALKIVS AKNHQS 216 
Gene Ontology
 GO:0044297; C:cell body; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0031941; C:filamentous actin; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0035374; F:chondroitin sulfate binding; IEA:Compara.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0051764; P:actin crosslink formation; IEA:Compara.
 GO:0051017; P:actin filament bundle assembly; IEA:Compara.
 GO:0071345; P:cellular response to cytokine stimulus; IEA:Compara.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0010977; P:negative regulation of neuron projection development; IEA:Compara.
 GO:0007399; P:nervous system development; IDA:MGI.
 GO:0048666; P:neuron development; IEA:Compara.
 GO:0051491; P:positive regulation of filopodium assembly; IEA:Compara.
 GO:0010976; P:positive regulation of neuron projection development; IEA:Compara.
 GO:0051260; P:protein homooligomerization; IEA:Compara.
 GO:0048678; P:response to axon injury; IEA:Compara. 
Interpro
 IPR006680; Amidohydro_1. 
Pfam
 PF01979; Amidohydro_1 
SMART
  
PROSITE
  
PRINTS