CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040649
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PRP40 pre-mRNA processing factor 40 homolog B (Yeast), isoform CRA_a 
Protein Synonyms/Alias
 Pre-mRNA-processing factor 40 homolog B 
Gene Name
 PRPF40B 
Gene Synonyms/Alias
 hCG_20201 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
170EYKSDTGKPYYYNNQacetylation[1, 2, 3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 892 AA 
Protein Sequence
MSVPDSGPRP PAAPAPFPPG PPMMPPPFMP PPGIPPPFPP MGLPPMSQRP PAIPPMPPGI 60
LPPMLPPMGA PPPLTQIPGM VPPMMPGMLM PAVPVTAATA PGADTASSAV AGTGPPRALW 120
SEHVAPDGRI YYYNADDKQS VWEKPSVLKS KAELLLSQCP WKEYKSDTGK PYYYNNQSKE 180
SRWTRPKDLD DLEVLVKQEA AGKQQQQLPQ TLQPQPPQPQ PDPPPVPPGP TPVPTGLLEP 240
EPGGSEDCDV LEATQPLEQG FLQQLEEGPS SSGQHQPQQE EEESKPEPER SGLSWSNREK 300
AKQAFKELLR DKAVPSNASW EQAMKMVVTD PRYSALPKLS EKKQAFNAYK AQREKEEKEE 360
ARLRAKEAKQ TLQHFLEQHE RMTSTTRYRR AEQTFGELEV WAVVPERDRK EVYDDVLFFL 420
AKKEKEQAKQ LRRRNIQALK SILDGMSSVN FQTTWSQAQQ YLMDNPSFAQ DHQLQNMDKE 480
DALICFEEHI RALEREEEEE RERARLRERR QQRKNREAFQ TFLDELHETG QLHSMSTWME 540
LYPAVSTDVR FANMLGQPGS TPLDLFKFYV EELKARFHDE KKIIKDILKD RGFCVEVNTA 600
FEDFAHVISF DKRAAALDAG NIKLTFNSLL EKAEARERER EKEEARRMRR REAAFRSMLR 660
QAVPALELGT AWEEVRERFV CDSAFEQITL ESERIRLFRE FLQVLETECQ HLHTKGRKHG 720
RKGKKHHHKR SHSPSGSESE EEELPPPSLR PPKRRRRNPS ESGSEPSSSL DSVESGGAAL 780
GGRGSPSSHL LGADHGLRKA KKPKKKTKKR RHKSNSPESE TDPEEKAGKE SDEKEQEQDK 840
DRELQQAELP NRSPGFGIKK EKTGWDTSES ELSEGELERR RRTLLQQLDD HQ 892 
Gene Ontology
  
Interpro
 IPR001202; WW_dom. 
Pfam
 PF00397; WW 
SMART
 SM00456; WW 
PROSITE
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 
PRINTS