CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004952
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NAD(+) kinase 
Protein Synonyms/Alias
 Unknown transcript 1 protein 
Gene Name
 UTR1 
Gene Synonyms/Alias
 YJR049C; J1655 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
470KYAHEANKVRNQAEPubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Specifically phosphorylates NAD in the presence of ATP, dATP, or CTP as phosphoryl donors. 
Sequence Annotation
 MOD_RES 499 499 Phosphoserine.
 MOD_RES 503 503 Phosphoserine.  
Keyword
 ATP-binding; Complete proteome; Kinase; NAD; NADP; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 530 AA 
Protein Sequence
MKENDMNNGV DKWVNEEDGR NDHHNNNNNL MKKAMMNNEQ IDRTQDIDNA KEMLRKISSE 60
SSSRRSSLLN KDSSLVNGNA NSGGGTSING TRGSSKSSNT HFQYASTAYG VRMLSKDISN 120
TKVELDVENL MIVTKLNDVS LYFLTRELVE WVLVHFPRVT VYVDSELKNS KKFAAGELCE 180
DSKCRESRIK YWTKDFIREH DVFFDLVVTL GGDGTVLFVS SIFQRHVPPV MSFSLGSLGF 240
LTNFKFEHFR EDLPRIMNHK IKTNLRLRLE CTIYRRHRPE VDPNTGKKIC VVEKLSTHHI 300
LNEVTIDRGP SPFLSMLELY GDGSLMTVAQ ADGLIAATPT GSTAYSLSAG GSLVCPTVNA 360
IALTPICPHA LSFRPIILPE SINLKVKVSM KSRAPAWAAF DGKDRIELQK GDFITICASP 420
YAFPTVEASP DEFINSISRQ LNWNVREQQK SFTHILSQKN QEKYAHEANK VRNQAEPLEV 480
IRDKYSLEAD ATKENNNGSD DESDDESVNC EACKLKPSSV PKPSQARFSV 530 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003951; F:NAD+ kinase activity; IDA:SGD.
 GO:0042736; F:NADH kinase activity; IDA:SGD.
 GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.
 GO:0019674; P:NAD metabolic process; IEA:InterPro.
 GO:0006741; P:NADP biosynthetic process; IDA:SGD. 
Interpro
 IPR017438; ATP-NAD_kinase_dom_1.
 IPR016064; ATP-NAD_kinase_PpnK-typ.
 IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
 IPR002504; PolyP/ATP_NADK_prd. 
Pfam
 PF01513; NAD_kinase 
SMART
  
PROSITE
  
PRINTS