UniProt Accession

 PPCT_MOUSE; P53808; Q9QZX0; Q9R058 

Genbank Protein ID

 AF151639; Z50024; AF114437 

Genbank Nucleotide ID

 AAF02537.1; CAA90328.1; AAF08346.1 

Protein Name

 Phosphatidylcholine transfer protein 

Protein Synonyms/Alias

 PC-TP; START domain-containing protein 2; StARD2; StAR-related lipid transfer protein 2 

Gene Name

 Pctp 

Gene Synonyms/Alias

 Stard2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
156	VIRVKQYKQSLAIES	ubiquitination	[1]
201	NGVPNFLKDMVKACQ	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule. 

Sequence Annotation

 DOMAIN 1 212 START.
 BINDING 72 72 Phosphatidylcholine (By similarity).
 BINDING 78 78 Phosphatidylcholine (By similarity).
 BINDING 157 157 Phosphatidylcholine (By similarity).
 MOD_RES 1 1 N-acetylmethionine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Lipid transport; Lipid-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 214 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0031210; F:phosphatidylcholine binding; ISS:UniProtKB.
 GO:0008525; F:phosphatidylcholine transporter activity; ISS:UniProtKB.
 GO:0008203; P:cholesterol metabolic process; IMP:MGI. 

Interpro

 IPR023393; START-like_dom.
 IPR002913; START_lipid-bd_dom. 

Pfam

 PF01852; START 

SMART

 SM00234; START 

PROSITE

 PS50848; START 

PRINTS