| Tag | Content |
|---|
| CPLM ID | CPLM-011159 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Endopolyphosphatase |
Protein Synonyms/Alias | Exopolyphosphatase; Phosphate metabolism protein 5 |
Gene Name | PPN1 |
Gene Synonyms/Alias | PHM5; YDR452W; D9461.37 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 6 | **MVVVGKSEVRNVS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths. The limited digestion products are 1 and 3 P(i) residues. |
Sequence Annotation | CARBOHYD 58 58 N-linked (GlcNAc...) (Potential).
CARBOHYD 505 505 N-linked (GlcNAc...) (Potential).
CARBOHYD 511 511 N-linked (GlcNAc...) (Potential).
CROSSLNK 6 6 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Complete proteome; Direct protein sequencing; Glycoprotein; Hydrolase; Isopeptide bond; Membrane; Metal-binding; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix; Ubl conjugation; Vacuole; Zymogen. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 674 AA |
Protein Sequence | MVVVGKSEVR NVSMSRPKKK SLIAILSTCV LFFLVFIIGA KFQYVSVFSK FLDDRGDNES 60
LQLLNDIEFT RLGLTPREPV IIKDVKTGKE RKLHGRFLHI TDIHPDPYYV EGSSIDAVCH 120
TGKPSKKKDV APKFGKAMSG CDSPVILMEE TLRWIKENLR DKIDFVIWTG DNIRHDNDRK 180
HPRTEAQIFD MNNIVADKMT ELFSAGNEED PRDFDVSVIP SLGNNDVFPH NMFALGPTLQ 240
TREYYRIWKN FVPQQQQRTF DRSASFLTEV IPGKLAVLSI NTLYLFKANP LVDNCNSKKE 300
PGYQLLLWFG YVLEELRSRG MKVWLSGHVP PIAKNFDQSC YDKFTLWTHE YRDIIIGGLY 360
GHMNIDHFIP TDGKKARKSL LKAMEQSTRV QQGEDSNEED EETELNRILD HAMAAKEVFL 420
MGAKPSNKEA YMNTVRDTYY RKVWNKLERV DEKNVENEKK KKEKKDKKKK KPITRKELIE 480
RYSIVNIGGS VIPTFNPSFR IWEYNITDIV NDSNFAVSEY KPWDEFFESL NKIMEDSLLE 540
DEMDSSNIEV GINREKMGEK KNKKKKKNDK TMPIEMPDKY ELGPAYVPQL FTPTRFVQFY 600
ADLEKINQEL HNSFVESKDI FRYEIEYTSD EKPYSMDSLT VGSYLDLAGR LYENKPAWEK 660
YVEWSFASSG YKDD 674 |
Gene Ontology | GO:0000329; C:fungal-type vacuole membrane; IMP:SGD. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005634; C:nucleus; IMP:SGD. GO:0000298; F:endopolyphosphatase activity; IMP:SGD. GO:0004309; F:exopolyphosphatase activity; IDA:SGD. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006798; P:polyphosphate catabolic process; IDA:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |