CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031578
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 
Protein Synonyms/Alias
 Protein Appl2; Similar to DIP13 beta (Predicted) 
Gene Name
 Appl2 
Gene Synonyms/Alias
 RGD1563028_predicted; rCG_48892 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
407PITSFGKKQESFYFSubiquitination[1]
426NSDTGYVKIVPKAAAubiquitination[1]
618KEIIEVQKDPEALARubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 662 AA 
Protein Sequence
MPAVDKLLLE EALQDSPQTR SLLSVFEEDA GTLTDYTNQL LQAMQRVYGA QNEMCLATQQ 60
LSRQLLAYEK QNFALGKGDE EVISTLHYFS KVMDELNGLH SELAKQLADT MVLPVIQFRE 120
KDLTEVSTLK DLFGLASNEH DLSMAKYSRL PKRKENERVK TDVAKEVAAA RRKQHLSSLQ 180
YYCALNALQY RKRAAMMEPL IGFAHGQINF FKKGAEMFSK SMDGFLSSVT DMVQSIQVEL 240
EAEADKMRVS QQELLSVSES VYTPDIDVAT PQINRNLIQK TGYLNLRNKT GLVTTTWERL 300
YFFTQGGNLM CQPRGAVAGG LIQDLDNCSV MAVDCEDRRY CFQISTPSGK PGIILQAESR 360
KEYEEWICAI NNISRQIYLT DNPEAVAIKL NQTALQAVTP ITSFGKKQES FYFSQNIKNS 420
DTGYVKIVPK AAASIPETEE LIAPGTPIQF DIVLPATEFL DQNRGSRRIN PFGETEDDSF 480
PDAEDSLLQQ MFIVRFLGSM AVKTDSTTEV IYEAMRQVLA ARAIHNIFRT TESHLMVTSQ 540
TLRLIDPQTQ VSRACFELTS VTQFAAHQEN KRLVGFVIRV PESTGEESLS TYIFESNSEG 600
EKICYAINLG KEIIEVQKDP EALARLMLSV PLTNDGKYVL LNDQADDTGG SPSDHRGAES 660
EA 662 
Gene Ontology
 GO:0010008; C:endosome membrane; IEA:Compara.
 GO:0016581; C:NuRD complex; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008283; P:cell proliferation; IEA:Compara. 
Interpro
 IPR027267; AH/BAR-dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR006020; PTyr_interaction_dom. 
Pfam
 PF00169; PH
 PF00640; PID 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN
 PS01179; PID 
PRINTS