CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022708
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA polymerase subunit gamma-2, mitochondrial 
Protein Synonyms/Alias
 DNA polymerase gamma accessory 55 kDa subunit; p55; Mitochondrial DNA polymerase accessory subunit; MtPolB; PolG-beta 
Gene Name
 Polg2 
Gene Synonyms/Alias
 Mtpolb 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
262ELGRKGSKLYYSFPWacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
 Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA. 
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; DNA replication; DNA-binding; DNA-directed DNA polymerase; Mitochondrion; Nucleotidyltransferase; Reference proteome; Transferase; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 459 AA 
Protein Sequence
MRCGGGARAC RRACRCWLSG YAGPADGTQQ PDAPEHAVAR EALVDLCRRR HFFSGTPQQL 60
STAALLSGCH ARFGPLGVEL RKNLASQWWS SMVVFREQVF AVDSLHQEPG SSQPRDSAFR 120
LVSPESIREI LQDREPSKEQ LVAFLENLLK TSGKLRATLL HGALEHYVNC LDLVNRKLPF 180
GLAQIGVCFH PVSNSNQTPS SVTRVGEKTE ASLVWFTPTR TSSQWLDFWL RHRLLWWRKF 240
AMSPSNFSSA DCQDELGRKG SKLYYSFPWG KEPIETLWNL GDQELLHTYP GNVSTIQGRD 300
GRKNVVPCVL SVSGDVDLGT LAYLYDSFQL AENSFARKKS LQRKVLKLHP CLAPIKVALD 360
VGKGPTVELR QVCQGLLNEL LENGISVWPG YSETVHSSLE QLHSKYDEMS VLFSVLVTET 420
TLENGLIQLR SRDTTMKEMM HISKLRDFLV KYLASASNV 459 
Gene Ontology
 GO:0042645; C:mitochondrial nucleoid; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003887; F:DNA-directed DNA polymerase activity; IDA:MGI.
 GO:0006281; P:DNA repair; TAS:MGI.
 GO:0006260; P:DNA replication; IC:MGI. 
Interpro
 IPR004154; Anticodon-bd.
 IPR027031; Gly-tRNA_synthase/POLG2.
 IPR027030; POLG2. 
Pfam
 PF03129; HGTP_anticodon 
SMART
  
PROSITE
  
PRINTS