| Tag | Content |
|---|
| CPLM ID | CPLM-023511 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glycogen phosphorylase, muscle form |
Protein Synonyms/Alias | Myophosphorylase |
Gene Name | Pygm |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 10 | RPLSDQDKRKQISVR | ubiquitination | [1] | | 29 | VENVSELKKNFNRHL | ubiquitination | [1] | | 42 | HLHFTLVKDRNVATP | ubiquitination | [1] | | 248 | TMRLWSAKAPNDFNL | ubiquitination | [1] | | 290 | NDNFFEGKELRLKQE | ubiquitination | [1] | | 316 | IRRFKSSKFGSRDPV | ubiquitination | [1] | | 364 | LERLDWDKAWDVTVK | ubiquitination | [1] | | 483 | EPHKFQNKTNGITPR | ubiquitination | [1] | | 521 | SDLDQLRKLLSYVDD | ubiquitination | [1] | | 618 | APGYHMAKMIIKLIT | ubiquitination | [1] | | 656 | YRVSLAEKVIPAADL | ubiquitination | [1] | | 754 | SSGFFSPKQPDLFKD | ubiquitination | [1] | | 783 | ADYEEYIKCQDKVSE | ubiquitination | [1] | | 811 | RNIATSGKFSSDRTI | ubiquitination | [1] | | 841 | RLPAPDEKI****** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. |
Sequence Annotation | BINDING 76 76 AMP (By similarity).
MOD_RES 2 2 N-acetylserine (By similarity).
MOD_RES 15 15 Phosphoserine; by PHK; in form
MOD_RES 473 473 Phosphotyrosine.
MOD_RES 681 681 N6-(pyridoxal phosphate)lysine (By |
Keyword | Acetylation; Allosteric enzyme; Carbohydrate metabolism; Complete proteome; Glycogen metabolism; Glycosyltransferase; Nucleotide-binding; Phosphoprotein; Pyridoxal phosphate; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 842 AA |
Protein Sequence | MSRPLSDQDK RKQISVRGLA GVENVSELKK NFNRHLHFTL VKDRNVATPR DYYFALAHTV 60
RDHLVGRWIR TQQHYYEKDP KRIYYLSLEF YMGRTLQNTM VNLALENACD EATYQLGLDM 120
EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEFGIFNQK ICGGWQMEEA 180
DDWLRYGNPW EKARPEFTLP VHFYGRVEHT SQGAKWVDTQ VVLAMPYDTP VPGYRNNVVN 240
TMRLWSAKAP NDFNLKDFNV GGYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV 300
VAATLQDIIR RFKSSKFGSR DPVRTNFDAF PDKVAIQLND THPSLAIPEL MRILVDLERL 360
DWDKAWDVTV KTCAYTNHTV LPEALERWPV HLMETLLPRH LQIIYEINQR FLNRVAAAFP 420
GDVDRLRRMS LVEEGAVKRI NMAHLCIAGS HAVNGVARIH SEILKKTIFK DFYELEPHKF 480
QNKTNGITPR RWLVLCNPGL AEVIAERIGE DYISDLDQLR KLLSYVDDEA FIRDVAKVKQ 540
ENKLKFSAYL EREYKVHINP NSLFDVQVKR IHEYKRQLLN CLHIITLYNR IKREPNRFMV 600
PRTIMIGGKA APGYHMAKMI IKLITAIGDV VNHDPAVGDR LRVIFLENYR VSLAEKVIPA 660
ADLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEENFF IFGMRVEDVE 720
RLDQRGYNAQ EYYDRIPELR QIIEQLSSGF FSPKQPDLFK DIVNMLMHHD RFKVFADYEE 780
YIKCQDKVSE LYKNPREWTR MVIRNIATSG KFSSDRTIAQ YAREIWGVEP SRQRLPAPDE 840
KI 842 |
Gene Ontology | GO:0008184; F:glycogen phosphorylase activity; IDA:MGI. GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. GO:0005980; P:glycogen catabolic process; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |