| Tag | Content |
|---|
| CPLM ID | CPLM-013648 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nostrin |
Protein Synonyms/Alias | BM247; Nitric oxide synthase trafficker; eNOS-trafficking inducer |
Gene Name | Nostrin |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 166 | QSMTQKEKQKLLNKL | acetylation | [1] | | 168 | MTQKEKQKLLNKLKK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane (By similarity). |
Sequence Annotation | DOMAIN 1 66 FCH.
DOMAIN 438 497 SH3.
MOD_RES 479 479 Phosphoserine (By similarity). |
Keyword | Cell membrane; Coiled coil; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Endocytosis; Membrane; Phosphoprotein; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 502 AA |
Protein Sequence | MRDPLTDCSY NKVYKSLKEF AQNGDNFCKQ ITSVLQQRAN LEISYAKGLQ KLAVKLSKAL 60
QSTKKNCLST AWAWASESMK SAADLHQKLG KAIELEAIKP THQVLSMQEK KRKSLDNEVE 120
KSANLVINNW NQQIKAKKKL MMSTKKHEAL FHLIESSKQS MTQKEKQKLL NKLKKSTEKL 180
EKEDESYYQK NMAGYSTRLK WESTLEKCYK SMLELEKERI QLLCNNLNQY SQHISLFGQT 240
LTTCHTQIHC AISKVDVEKD IQALMEETAV LSLENKSELL LADYFEEDPK NPMDKERRKS 300
LIKPKLWRLQ KDIEKASRDK EGLEQKLKAL ASSASFSDAK SQKDAETLMD ENSLKLDLLQ 360
ANSYKLSTVL ADLEQRPKPC HPCSNCIFKW KEKEHSHSYV KISRPLLTKR LEKAESKAPA 420
GEQNNPSSSR PGSSVSQGNN QLCKALYTFQ ARQDDELNLE KGDIVTIHEK KEEGWWFGSL 480
NGKKGHFPAA YVEELPPKAG QA 502 |
Gene Ontology | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:Compara. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:Compara. GO:0006897; P:endocytosis; IEA:UniProtKB-KW. GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |