CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-029097
UniProt Accession
A6NGI5_HUMAN
;
A6NGI5
Genbank Protein ID
AC098691
;
BX323048
Genbank Nucleotide ID
Protein Name
Probable ATP-dependent DNA helicase HFM1
Protein Synonyms/Alias
Gene Name
HFM1
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
768
VGLDIQQ
K
LTVFYLE
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
1114 AA
Protein Sequence
MEVPLPWLNI KIVYMAPIKA LCSQRFDDWK EKFGPIGLNC KELTGDTVMD DLFEIQHAHI 60
IMTTPEKWDS MTRKWRDNSL VQLVRLFLID EVHIVKDENR GPTLEVVVSR MKTVQSVSQT 120
LKNTSTAIPM RFVAVSATIP NAEDIAEWLS DGERPAVCLK MDESHRPVKL QKVVLGFPCS 180
SNQTEFKFDL TLNYKIASVI QMYSDQKPTL VFCATRKGVQ QAASVLVKDA KFIMTVEQKQ 240
RLQKYAYSVR DSKLRDILKD GAAYHHAGME LSDRKVVEGA FTVGDLPVLF TTSTLAMGVN 300
LPAHLVVIKS TMHYAGGLFE EYSETDILQM IGRAGRPQFD TTATAVIMTR LSTRDKYIQM 360
LACRDTVESS LHRHLIEHLN AEIVLHTITD VNIAVEWIRS TLLYIRALKN PSHYGFASGL 420
NKDGIEAKLQ ELCLKNLNDL SSLDLIKMDE GVNFKPTEAG RLMAWYYITF ETVKKFYTIS 480
GKETLSDLVT LIAGCKEFLD IQLRINEKKT LNTLNKDPNR ITIRFPMEGR IKTREMKVNC 540
LIQAQLGCIP IQDFALTQDT AKIFRHGSRI TRWLSDFVAA QEKKFAVLLN SLILAKCFRC 600
KLWENSLHVS KQLEKIGITL SNAIVNAGLT SFKKIEETDA RELELILNRH PPFGTQIKET 660
VMYLPKYELK VEQITRYSDT TAEILVTVIL RNFEQLQTKR TASDSHYVTL IIGDADNQVV 720
YLHKITDSVL LKAGSWAKKI AVKRALKSED LSINLISSEF VGLDIQQKLT VFYLEPKRFG 780
NQITMQRKSE TQISHSKHSD ISTIAGPNKG TTASKKPGNR ECNHLCKSKH TCGHDCCKIG 840
VAQKSEIKES TISSYLSDLR NRNAVSSVPP VKRLKIQMNK SQSVDLKEFG FTPKPSLPSI 900
SRSEYLNISE LPIMEQWDQP EIYGKVRQEP SEYQDKEVLN VNFELGNEVW DDFDDENLEV 960
TSFSTDTEKT KISGFGNTLS SSTRGSKLPL QESKSKFQRE MSNSFVSSHE MSDISLSNSA 1020
MPKFSASSMT KLPQQAGNAV IVHFQERKPQ NLSPEIEKQC FTFSEKNPNS SNYKKVDFFI 1080
RNSECKKEVD FSMYHPDDEA DEMKSLLGIF DGIF 1114
Gene Ontology
GO:0005524
; F:ATP binding; IEA:InterPro.
GO:0008026
; F:ATP-dependent helicase activity; IEA:InterPro.
GO:0003676
; F:nucleic acid binding; IEA:InterPro.
Interpro
IPR011545
; DNA/RNA_helicase_DEAD/DEAH_N.
IPR014001
; Helicase_ATP-bd.
IPR001650
; Helicase_C.
IPR027417
; P-loop_NTPase.
IPR004179
; Sec63-dom.
Pfam
PF00270
; DEAD
PF00271
; Helicase_C
PF02889
; Sec63
SMART
SM00490
; HELICc
SM00973
; Sec63
PROSITE
PS51192
; HELICASE_ATP_BIND_1
PS51194
; HELICASE_CTER
PRINTS