CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026999
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG1845 
Protein Synonyms/Alias
 GH12223p 
Gene Name
 Br140 
Gene Synonyms/Alias
 CG1845; Dmel_CG1845 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
12FDAVEYCKGVKTQQSacetylation[1]
81HSTPRPHKDHPTPGGacetylation[1]
462AHTPADAKLKMNVPDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1430 AA 
Protein Sequence
MGLDFDAVEY CKGVKTQQSQ PPFACPVRGC DRSYKTIMGL QYHLMKYDHD NPQPLTPVLT 60
PSRKKARSRS GGHHSTPRPH KDHPTPGGGG AEARNGCSSA SAGGGSASGV SARQYANPES 120
LVSYNEEEAT VTFNLDGKSV RLGIDDALPL VEDEEFAALV ARGCILNADA PPLEENAPWA 180
RVQVPVARVA EIPDYRVSDA PPRPLAYYRF IEKSLEELDG EVEYDVDEED SAWLEHMNEE 240
RQRLGLNAVG IDTMELLMDR LEKESHFQAA ANGTPTGVEV DDDAVCCICL DGECQNTNVI 300
LFCDMCNLAV HQDCYGVPYI PEGQWLCRRC LQSPSKPVNC VLCPNAGGAF KQTDHGQWAH 360
VVCALWIPEV RFANTVFLEP IDSIETIPPA RWRLTCYVCK EKGLGACIQC HRNSCYAAFH 420
VTCAQQAGLY MTMDTVKDGH NDSSMHVQKF AYCHAHTPAD AKLKMNVPDF EDTRHKMKEA 480
RKALAKKRST APVVLIPTIP PDRVQEIATM VTMQRKKEFL DRIIAYWTLK RHYRNGVPLL 540
RRLQSQGNNH GVIQRNGIEG SPDTGELYRQ LKYWQCLRQD LERARLLCEL VRKREKLKVA 600
FVRISEEVVM LQLNPLEAAL NKLLDALEAR DSMQIFREPV DTSEVPDYTD IVKQPMDLGT 660
MRAKLKECQY NSLEQLEADF DLMIQNCLAY NNKDTVFYRA GIRMRDQAAP LFVQVRKELQ 720
RDGLLARSQR YHVDHVEAEV EQELRLLLAA PASEGIVQKL LILADKSQVL KNPTYRTKKI 780
KQIRLEISRM RKSLQKARFA ARHSSHANQS QSDDEDTLGG SPSKKRTRKR FNSSGVDMEL 840
GHDDDDEEED SDEDSMGEDT VSKDLLNSTQ TPPCSPIKSL NNSSSPVGIN RRTAILLTRK 900
AQAALKRPSE PLTTPVKEEQ HNSQSSNTQS TSGSSSSVTT AATAASSGAG TLNHVLSSAP 960
PTASSFALTQ NNSSGGGALA SGTGIGGSSS AGTAAAASLT STALAMNSKL SANLPVKSPK 1020
RPGRYRRVPE VRHSSSMSPK KSPNPAVTVS QALPMPETLP FERIPDSFRV YRANNQRDVS 1080
DSDDAPSQSS SPCSSCSDFS MSGSCSDFDS DEASEGDADG DPDRDGGRSR SEERDSTSQE 1140
GTTDAMDMQH ASLNNVQGNN GNMAISSSSG GSGGSSSEDD ELEERPLSAR QNKPMKVGTR 1200
GTPTPTTMAR AVALSAGRGR GKRRSNLSES TSSTATPPPL RRAGKLRSAT PNASPLVNNI 1260
KARRNTTAAG SAPLTNNNRS KHSEDSASSE RHNNHSHGQK PALEPLQLVW AKCRGYPWYP 1320
ALILDPKTPK GFVYNGVPLP APPTDVLALR KNCLDEIVFL VLFFDVKRTW QWLPANKLDI 1380
LGIDKQLDQQ KLVESRKPAE RKAVKKAYQD ALHYQSQVSD LEGQGPDPIM 1430 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0033563; P:dorsal/ventral axon guidance; IMP:FlyBase. 
Interpro
 IPR001487; Bromodomain.
 IPR019542; Enhancer_polycomb-like_N.
 IPR000313; PWWP.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00439; Bromodomain
 PF10513; EPL1
 PF00855; PWWP 
SMART
 SM00297; BROMO
 SM00249; PHD
 SM00293; PWWP
 SM00355; ZnF_C2H2 
PROSITE
 PS50014; BROMODOMAIN_2
 PS50812; PWWP
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS
 PR00503; BROMODOMAIN.