CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028591
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HLA class II histocompatibility antigen, DQ beta 2 chain 
Protein Synonyms/Alias
 cDNA FLJ40688 fis, clone THYMU2024185, highly similar to HLA class II histocompatibility antigen, DX beta chain 
Gene Name
 HLA-DQB2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
155DFYPAQIKVRWFRNDubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Immunity; Membrane; MHC II; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 275 AA 
Protein Sequence
MALQIPGGFW AAAVTVMLVM LSTPVAEARD FPKDFLVQFK GMCYFTNGTE RVRGVARYIY 60
NREEYGRFDS DVGEFQAVTE LGRSIEDWNN YKDFLEQERA AVDKVCRHNY EAELRTTLQR 120
QVEPTVTISP SRTEALNHHN LLVCSVTDFY PAQIKVRWFR NDQEETAGVV STSLIRNGDW 180
TFQILVMLEI TPQRGDIYTC QVEHPSLQSP ITVEWRAQSE SAQSKMLSGI GGFVLGLIFL 240
GLGLIIRHRG QKGPRGPPPA GNISAMIQSG ERAQA 275 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR000353; MHC_II_b_N. 
Pfam
 PF07654; C1-set
 PF00969; MHC_II_beta 
SMART
 SM00407; IGc1
 SM00921; MHC_II_beta 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS