UniProt Accession

 HXT4_YEAST; P32467; D3DL44 

Genbank Protein ID

 M81960; X67321; U00060; BK006934 

Genbank Nucleotide ID

 AAA20997.1; CAA47735.1; AAB68932.1; DAA06788.2 

Protein Name

 Low-affinity glucose transporter HXT4 

Protein Synonyms/Alias

 Low-affinity glucose transporter LGT1 

Gene Name

 HXT4 

Gene Synonyms/Alias

 LGT1; RAG1; YHR092C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
45	KAERDDMKDFDENHE	ubiquitination	[1, 2, 3, 4]

Reference

 [1] A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
 Hitchcock AL, Auld K, Gygi SP, Silver PA.
 Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12735-40. [PMID: 14557538]
 [2] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [3] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [4] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Low-affinity glucose transporter. Can also transport xylose. 

Sequence Annotation

 CARBOHYD 425 425 N-linked (GlcNAc...) (Potential).
 CROSSLNK 45 45 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Cell membrane; Complete proteome; Glycoprotein; Isopeptide bond; Membrane; Reference proteome; Repeat; Sugar transport; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 576 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0005353; F:fructose transmembrane transporter activity; TAS:SGD.
 GO:0005355; F:glucose transmembrane transporter activity; IDA:SGD.
 GO:0015578; F:mannose transmembrane transporter activity; TAS:SGD.
 GO:0015146; F:pentose transmembrane transporter activity; IMP:SGD. 

Interpro

 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 

Pfam

 PF00083; Sugar_tr 

SMART

  

PROSITE

 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 

PRINTS

 PR00171; SUGRTRNSPORT.