CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041003
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myc proto-oncogene protein 
Protein Synonyms/Alias
  
Gene Name
 Myc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
163AAKLVSEKLASYQAAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 453 AA 
Protein Sequence
LNFLWEVENP TVTTMPLNVS FANRNYDLDY DSVQPYFICD EEENFYHQQQ QSELQPPAPS 60
EDIWKKFELL PTPPLSPSRR SGLCSPSYVA VATSFSPRED DDGGGGNFST ADQLEMMTEL 120
LGGDMVNQSF ICDPDDETFI KNIIIQDCMW SGFSAAAKLV SEKLASYQAA RKDSTSLSPA 180
RGHSVCSTSS LYLQDLTAAA SECIDPSVVF PYPLNDSSSP KSCTSSDSTA FSSSSDSLLS 240
SESSPRATPE PLVLHEETPP TTSSDSEEEQ DDEEEIDVVS VEKRQPPAKR SESGSSPSRG 300
HSKPPHSPLV LKRCHVSTHQ HNYAAPPSTR KDYPAAKRAK LDSGRVLKQI SNNRKCSSPR 360
SSDTEENDKR RTHNVLERQR RNELKRSFFA LRDQIPELEN NEKAPKVVIL KKATAYILSV 420
QADEHKLISE KDLLRKRREQ LKHKLEQLRN SGA 453 
Gene Ontology
 GO:0030424; C:axon; IEA:Compara.
 GO:0016604; C:nuclear body; IEA:Compara.
 GO:0005819; C:spindle; IEA:Compara.
 GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0006309; P:apoptotic DNA fragmentation; IEA:Compara.
 GO:0001783; P:B cell apoptotic process; IEA:Compara.
 GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Compara.
 GO:0035690; P:cellular response to drug; IEA:Compara.
 GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Compara.
 GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Compara.
 GO:0042474; P:middle ear morphogenesis; IEA:Compara.
 GO:0032091; P:negative regulation of protein binding; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043473; P:pigmentation; IEA:Compara.
 GO:0002904; P:positive regulation of B cell apoptotic process; IEA:Compara.
 GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0016485; P:protein processing; IEA:Compara.
 GO:0001836; P:release of cytochrome c from mitochondria; IEA:Compara.
 GO:0043279; P:response to alkaloid; IEA:Compara.
 GO:0006974; P:response to DNA damage stimulus; IEA:Compara.
 GO:0009314; P:response to radiation; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:Compara. 
Interpro
 IPR011598; bHLH_dom.
 IPR003327; Myc-LZ.
 IPR002418; Tscrpt_reg_Myc.
 IPR012682; Tscrpt_reg_Myc_N. 
Pfam
 PF00010; HLH
 PF02344; Myc-LZ
 PF01056; Myc_N 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS
 PR00044; LEUZIPPRMYC.