CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045242
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Branched-chain-amino-acid aminotransferase 
Protein Synonyms/Alias
  
Gene Name
 BCAT2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
36LQLEMTQKPHKKPGPacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
 MOD_RES 221 221 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Amino-acid biosynthesis; Aminotransferase; Branched-chain amino acid biosynthesis; Complete proteome; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 445 AA 
Protein Sequence
IWARKLLSVP WLLCGPRRYA SSSFKAADLQ LEMTQKPHKK PGPGEPLVFG KTFTDHMLMV 60
EWNDKGWGQP RIQPFQNLTL HPASSSLHYS LQLFEGMKAF KGKDQQVRLF RPWLNMDRML 120
RSAMRLCLPS FDKLELLECI RRLIEVDKDW VPDAAGTSLY VRPVLIGNEP SLGVSQPTRA 180
LLFVILCPVG AYFPGGSVTP VSLLADPAFI RAWVGGVGNY KLGGNYGPTV LVQQEALKRG 240
CEQVLWLYGP DHQLTEVGTM NIFVYWTHED GVLELVTPPL NGVILPGVVR QSLLDMAQTW 300
GEFRVVERTI TMKQLLRALE EGRVREVFGS GTACQVCPVH RILYKDRNLH IPTMENGPEL 360
ILRFQKELKE IQYQEQIMAF LIEALESGLS VLLCGLENPL GLNHPFLGAP GALDMSSALE 420
TPSCDPLRLL GALYGIRAHE WMFPV 445 
Gene Ontology
 GO:0052656; F:L-isoleucine transaminase activity; IEA:EC.
 GO:0052654; F:L-leucine transaminase activity; IEA:EC.
 GO:0052655; F:L-valine transaminase activity; IEA:EC.
 GO:0009082; P:branched-chain amino acid biosynthetic process; IEA:UniProtKB-KW. 
Interpro
 IPR001544; Aminotrans_IV.
 IPR018300; Aminotrans_IV_CS.
 IPR005786; B_amino_transII. 
Pfam
 PF01063; Aminotran_4 
SMART
  
PROSITE
 PS00770; AA_TRANSFER_CLASS_4 
PRINTS