CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044386
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein FAM83H 
Protein Synonyms/Alias
  
Gene Name
 FAM83H 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51PTPFSFPKRAHLLFPubiquitination[1, 2]
135HLEMDAFKRHSFATEubiquitination[3]
202RPQGLFEKLRGGRAGubiquitination[1, 2, 3]
366VPAAFPTKVPVPGPGubiquitination[3]
391PEEPGLAKQDSFRSRubiquitination[3]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 906 AA 
Protein Sequence
XRILFAQSEP LVPSAAALAR MDAYALAPYA GAGPLVGVPG VGAPTPFSFP KRAHLLFPPP 60
REEGLGFPSF LDPDRHFLSA FRREEPPRMP GGALEPHAGL RPLSRRLEAE AGPAGELAGA 120
RGFFQARHLE MDAFKRHSFA TEGAGAVENF AAARQVSRQT FLSHGDDFRF QTSHFHRDQL 180
YQQQYQWDPQ LTPARPQGLF EKLRGGRAGF ADPDDFTLGA GPRFPELGPD GHQRLDYVPS 240
SASREVRHGS DPAFAPGPRG LEPSGAPRPN LTQRFPCQAA ARPGPDPAPE AEPERRGGPE 300
GRAGLRRWRL ASYLSGCHGE DGGDDGLPAP MEAEAYEDDV LAPGGRAPAG DLLPSAFRVP 360
AAFPTKVPVP GPGSGGNGPE REGPEEPGLA KQDSFRSRLN PLVQRSSRLR SSLIFSTSQA 420
EGAAGAAAAT EKVQLLHKEQ TVSETLGPGG EAVRSAASTK VAELLEKYKG PARDPGGGAG 480
AITVASHSKA VVSQAWREEV AAPGAVGGER RSLESCLLDL RDSFAQQLHQ EAERQPGAAS 540
LTAAQLLDTL GRSGSDRLPS RFLSAQSHST SPQGLDSPLP LEGSGAHQVL HNESKGSPTS 600
AYPERKGSPT PGFSTRRGSP TTGFIEQKGS PTSAYPERRG SPVPPVPERR SSPVPPVPER 660
RGSLTLTISG ESPKAGPAEE GPSGPMEVLR KGSLRLRQLL SPKGERRMED EGGFPVPQEN 720
GQPESPRRLS LGQGDSTEAA TEERGPRARL SSATANALYS SNLRDDTKAI LEQISAHGQK 780
HRAVPAPSPG PTHNSPELGR PPAAGVLAPD MSDKDKCSAI FRSDSLGTQG RLSRTLPASA 840
EERDRLLRRM ESMRKEKRVY SRFEVFCKKE EASSPGAGEG PAEEGTRDSK VGKFVPKILG 900
TFKSKK 906 
Gene Ontology
  
Interpro
 IPR012461; DUF1669. 
Pfam
  
SMART
  
PROSITE
  
PRINTS