UniProt Accession

 B7Z1N3_HUMAN; B7Z1N3 

Genbank Protein ID

 AL021578; AK293686; AK299013 

Genbank Nucleotide ID

 BAH11569.1; BAH12928.1 

Protein Name

 GPI transamidase component PIG-T 

Protein Synonyms/Alias

 cDNA FLJ51050, highly similar to GPI transamidase component PIG-T; cDNA FLJ61680, highly similar to GPI transamidase component PIG-T 

Gene Name

 PIGT 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
77	LNIQLKWKRPPENEA	ubiquitination	[1]
103	VSGYGLQKGELSTLL	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 316 AA 

Protein Sequence

Gene Ontology

 GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:Compara.
 GO:0042765; C:GPI-anchor transamidase complex; IEA:Compara.
 GO:0003923; F:GPI-anchor transamidase activity; IEA:Compara.
 GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
 GO:0051402; P:neuron apoptotic process; IEA:Compara.
 GO:0030182; P:neuron differentiation; IEA:Compara. 

Interpro

 IPR007245; PIG-T. 

Pfam

 PF04113; Gpi16 

SMART

  

PROSITE

  

PRINTS