| Tag | Content |
|---|
| CPLM ID | CPLM-004251 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA repair protein RAD9 |
Protein Synonyms/Alias | |
Gene Name | RAD9 |
Gene Synonyms/Alias | YDR217C; YD9934.02C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1139 | LSLDSPSKGGIIKSN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase. |
Sequence Annotation | DOMAIN 994 1122 BRCT.
MOD_RES 26 26 Phosphoserine.
MOD_RES 56 56 Phosphoserine.
MOD_RES 205 205 Phosphoserine.
MOD_RES 218 218 Phosphothreonine.
MOD_RES 248 248 Phosphoserine.
MOD_RES 312 312 Phosphoserine.
MOD_RES 315 315 Phosphoserine.
MOD_RES 462 462 Phosphoserine.
MOD_RES 471 471 Phosphothreonine.
MOD_RES 474 474 Phosphothreonine.
MOD_RES 568 568 Phosphoserine.
MOD_RES 729 729 Phosphoserine. |
Keyword | 3D-structure; Cell cycle; Complete proteome; DNA damage; DNA replication inhibitor; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1309 AA |
Protein Sequence | MSGQLVQWKS SPDRVTQSAI KEALHSPLAD GDMNEMNVPV DPLENKVNST NIIEGSPKAN 60
PNPVKFMNTS EIFQKSLGLL DESPRHDDEL NIEVGDNDRP NANILHNERT PDLDRIANFF 120
KSNRTPGKEN LLTKYQSSDL EDTPLMLRKK MTFQTPTDPL EQKTFKKLKS DTGFCYYGEQ 180
NDGEENASLE VTEADATFVQ MAERSADNYD CALEGIVTPK RYKDELSKSG GMQDERVQKT 240
QIMISAESPN SISSYDKNKI TGNGRTTRNV NKVFNNNEDN IGAIEEKNPV KKKSENYSSD 300
DLRERNNQII QSNESEEINE LEKNLNVSGR ENDVNNLDID INSAVSGTPS RNNAEEEMYS 360
SESVNNREPS KKWIFRYSKD KTENNSNRST QIVNNPRTQE MPLDSISIDT QPLSKSFNTE 420
TNNELETQII VSSLSQGISA QKGPVFHSTG QTEEIKTQII NSPEQNALNA TFETPVTLSR 480
INFEPILEVP ETSSPSKNTM SKPSNSSPIP KEKDTFNIHE REVETNNVFS NDIQNSSNAA 540
TRDDIIIAGS SDFNEQKEIT DRIYLQLSGK QISDSGSDET ERMSPNELDT KKESTIMSEV 600
ELTQELPEVE EQQDLQTSPK KLVVEEETLM EIKKSKGNSL QLHDDNKECN SDKQDGTESL 660
DVALIEHESK GQSSELQKNL MQLFPSESQE IIQNRRTIKR RQKDTIEIGE EEENRSTKTS 720
PTKHLKRNSD LDAASIKREP SCSITIQTGE TGSGKDSKEQ SYVFPEGIRT ADNSFLSKDD 780
IIFGNAVWCQ YTWNYKFYPG ILLEVDTNQD GCWIYFETGR SLTKDEDIYY LDIRIGDAVT 840
FDGNEYVVVG LECRSHDLNI IRCIRGYDTV HLKKKNASGL LGKRTLIKAL SSISLDLSEW 900
AKRAKIILED NEKNKGDAYR YLRHPIRGRK SMTNVLSPKK HTDDEKDINT HTEVYNNEIE 960
SSSEKKEIVK KDSRDALAEH AGAPSLLFSS GEIRTGNVFD KCIFVLTSLF ENREELRQTI 1020
ESQGGTVIES GFSTLFNFTH PLAKSLVNKG NTDNIRELAL KLAWKPHSLF ADCRFACLIT 1080
KRHLRSLKYL ETLALGWPTL HWKFISACIE KKRIVPHLIY QYLLPSGESF RLSLDSPSKG 1140
GIIKSNNIFS FYTQFLRGSN LRDQICGVKK MLNDYIVIVW GRSELDSFVK FAFACLSAGR 1200
MLTIDLPNID VDDTEPLLNA LDSLVPRIGS ELSNRKLKFL IYANENNGKS QMKLLERLRS 1260
QISLKFKKFN YIFHTESKEW LIQTIINEDT GFHDDITDND IYNTISEVR 1309 |
Gene Ontology | GO:0000785; C:chromatin; IDA:SGD. GO:0005634; C:nucleus; IC:SGD. GO:0003690; F:double-stranded DNA binding; IDA:SGD. GO:0042393; F:histone binding; IDA:SGD. GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD. GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:SGD. GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. GO:0006289; P:nucleotide-excision repair; IMP:SGD. GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |