CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037121
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 BRCA1-associated RING domain protein 1 
Protein Synonyms/Alias
  
Gene Name
 BARD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
16KVRYVVSKASVQTQPubiquitination[1]
27QTQPAIKKDASAQQDubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MWFSPRSKKV RYVVSKASVQ TQPAIKKDAS AQQDSYEFVS PSPPADVSER AKKASARSGK 60
KQKKKTLAEI NQKWNLEAEK EDGEFDSKEE SKQKLVSFCS QPSVISSPQI NGEIDLLASG 120
SLTESECFGS LTEVSLPLAE QIESPDTKSR NEVVTPEKVC KNYLTSKKSL PLENNGKRGH 180
HNRLSSPISK RCRTSILSTS GDFVKQTVPS ENIPLPECSS PPSCKRKVGG TSGRKNSNMS 240
DEFISLSPGT PPSTLSSSSY RRVMSSPSAM KLLPNMAVKR NHRGETLLHI ASIKGDIPSV 300
EYLLQNGSDP NVKDHAGWTP LHEACNHGHL KVVELLLQHK ALVNTTGYQN DSPLHDAAKN 360
GHVDIVKLLL SYGASRNAVN IFGLRPVDYT DDESMKSLLL LPEKNESSSA SHCSVMNTGQ 420
RRDGPLVLIG SGLSSEQQKM LSELAVILKA KKYTEFDSTV THVVVPGDAV QSTLKCMLGI 480
LNGCWILKFE WVKACLRRKV CEQEEKYEIP EGPRRSRLNR EHCQSCLMDA TSICGEPSNT 540
IQRTTLLSSS LQVGARSSVE SPSQTVT 567 
Gene Ontology
  
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001357; BRCT_dom. 
Pfam
 PF00023; Ank
 PF12796; Ank_2
 PF00533; BRCT 
SMART
 SM00248; ANK
 SM00292; BRCT 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50172; BRCT 
PRINTS
 PR01415; ANKYRIN.