UniProt Accession

 C9IYX7_HUMAN; C9IYX7 

Genbank Protein ID

 AC106724; AC117384 

Genbank Nucleotide ID

  

Protein Name

 Neprilysin 

Protein Synonyms/Alias

  

Gene Name

 MME 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
93	YACGGWLKRNVIPET	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 119 AA 

Protein Sequence

Gene Ontology

 GO:0030424; C:axon; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0016020; C:membrane; IEA:Compara.
 GO:0044306; C:neuron projection terminus; IEA:Compara.
 GO:0008021; C:synaptic vesicle; IEA:Compara.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0042277; F:peptide binding; IEA:Compara.
 GO:0050435; P:beta-amyloid metabolic process; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:Compara.
 GO:0019233; P:sensory perception of pain; IEA:Compara. 

Interpro

 IPR000718; Peptidase_M13.
 IPR008753; Peptidase_M13_N. 

Pfam

 PF05649; Peptidase_M13_N 

SMART

  

PROSITE

  

PRINTS