CPLM-003699

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-003699

UniProt Accession

GPHRB_HUMAN; P0CG08; A6NN37; B2RUV3; B3KMN3; Q53FQ9; Q5T2V8; Q5T5P5; Q659E2; Q6NVY5; Q9P0S4; Q9Y302

Genbank Protein ID

U78723; AL445591; BX537254; BX537254; AL445591; AL133020; AF151035

Genbank Nucleotide ID

AAF21463.1; CAH72386.1; CAH72386.1; CAI18821.1; CAI18821.1; CAH56393.1; AAF36121.1

Protein Name

Golgi pH regulator B

Protein Synonyms/Alias

Protein GPR89B

Gene Name

GPR89B

Gene Synonyms/Alias

GPHRB; HSPC201

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
203	TMDMIISKKKRMAMA	ubiquitination	[1]
272	TADLYATKERIEYSK	ubiquitination	[1]
279	KERIEYSKTFKGKYF	ubiquitination	[1]

Reference

[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]

Functional Description

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (By similarity).

Sequence Annotation

CARBOHYD 180 180 N-linked (GlcNAc...) (Potential).
CARBOHYD 243 243 N-linked (GlcNAc...) (Potential).

Keyword

Complete proteome; Glycoprotein; Golgi apparatus; Ion channel; Ion transport; Membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

455 AA

Protein Sequence

MSFLIDSSIM ITSQILFFGF GWLFFMRQLF KDYEIRQYVV QVIFSVTFAF SCTMFELIIF 60
EILGVLNSSS RYFHWKMNLC VILLILVFMV PFYIGYFIVS NIRLLHKQRL LFSCLLWLTF 120
MYFFWKLGDP FPILSPKHGI LSIEQLISRV GVIGVTLMAL LSGFGAVNCP YTYMSYFLRN 180
VTDTDILALE RRLLQTMDMI ISKKKRMAMA RRTMFQKGEV HNKPSGFWGM IKSVTTSASG 240
SENLTLIQQE VDALEELSRQ LFLETADLYA TKERIEYSKT FKGKYFNFLG YFFSIYCVWK 300
IFMATINIVF DRVGKTDPVT RGIEITVNYL GIQFDVKFWS QHISFILVGI IIVTSIRGLL 360
ITLTKFFYAI SSSKSSNVIV LLLAQIMGMY FVSSVLLIRM SMPLEYRTII TEVLGELQFN 420
FYHRWFDVIF LVSALSSILF LYLAHKQAPE KQMAP 455

Gene Ontology

GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.

Interpro

IPR025969; ABA_GPCR_dom.
IPR022535; Golgi_pH-regulator_cons_dom.
IPR015672; GPCR89-rel.

Pfam

PF12430; ABA_GPCR
PF12537; DUF3735

SMART

PROSITE

PRINTS