| Tag | Content |
|---|
| CPLM ID | CPLM-014755 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein phosphatase 1 regulatory subunit 29 |
Protein Synonyms/Alias | Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2; Leucine-rich repeat and fibronectin type-III domain-containing protein 6; Leucine-rich repeat-containing protein 62 |
Gene Name | Elfn2 |
Gene Synonyms/Alias | Kiaa1904; Lrrc62; Ppp1r29 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 480 | IPSMVGEKLPASKGL | ubiquitination | [1] | | 485 | GEKLPASKGLEAGLD | ubiquitination | [1] | | 499 | DTPKVATKGNYIEVR | ubiquitination | [1] | | 735 | SQRVSFLKPLTRSKR | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes (By similarity). |
Sequence Annotation | REPEAT 56 77 LRR 1.
REPEAT 80 101 LRR 2.
REPEAT 104 125 LRR 3.
REPEAT 128 149 LRR 4.
REPEAT 152 173 LRR 5.
DOMAIN 185 247 LRRCT.
DOMAIN 292 379 Fibronectin type-III.
MOD_RES 475 475 Phosphoserine.
MOD_RES 622 622 Phosphoserine.
CARBOHYD 54 54 N-linked (GlcNAc...) (Potential).
CARBOHYD 80 80 N-linked (GlcNAc...) (Potential).
CARBOHYD 85 85 N-linked (GlcNAc...) (Potential).
CARBOHYD 117 117 N-linked (GlcNAc...) (Potential).
CARBOHYD 205 205 N-linked (GlcNAc...) (Potential).
CARBOHYD 247 247 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Leucine-rich repeat; Membrane; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 823 AA |
Protein Sequence | MLRLGLCAAA LLCVCQPGAV RADCWLIEGD KGYVWLAICS QNQPPYETIP QHINSTVHDL 60
RLNENKLKAV LYSSLNRFGN LTDLNLTKNE ISYIEDGAFL GQTSLQVLQL GYNRLSNLTE 120
GMLRGMSRLQ FLFVQHNLIE VVTPTAFSEC PSLISIDLSS NRLSRLDGAT FASLASLMVC 180
ELAGNPFNCE CDLFGFLAWL VVFNNVTKNY DRLQCESPRE FAGYPLLVPR PYHSLNAITV 240
LQAKCRNGSM PARPVSHPTP YSTDAQREPD ENSGFNPDEI LSVEPPASST TDASAGPAIK 300
LHQVTFTSAT LVVIIPHPYS KMYVLVQYNN SYFSDVMTLK NKKEIVTLDK LRAHTEYTFC 360
VTSLRNSRRF NHTCLTFTTR DLVPGDLAPS TSTTTHYIMT ILGCLFGMVI VLGAVYYCLR 420
KRRMQEEKQK SVNVKKTILE MRYGADVDAG SIVHAAQKLG EPPVLPVARM SSIPSMVGEK 480
LPASKGLEAG LDTPKVATKG NYIEVRTGAA GDSLARPEEE LPEIENGQGS AAEISTIAKE 540
VDKVNQIINN CIDALKLDSA SFLGGGGGGG GGGDSDLAFE CQSLPAAPAA SSAATPGALE 600
RPSFLSPPYK ESSHHPLQRQ LSADAAVSRK TCSVSSSGSI KSAKVFSLDV PDHPTPTGLA 660
KSDSKYIEKG SPLNSPLDRL PLVPTGSSGS SGGGGGIHHL EVKPAYHCSE HRHSFPALYY 720
EEGADSLSQR VSFLKPLTRS KRDSTYSQLS PRHYYSGYSS SPEYSSESTH KIWERFRPYK 780
KHHREEVYMA AGHALRKKVQ FAKDEDLHDI LDYWKGVSAQ QKL 823 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0019902; F:phosphatase binding; ISS:UniProtKB. GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |