Tag | Content |
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CPLM ID | CPLM-006430 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar RNA-associated protein 20 |
Protein Synonyms/Alias | U3 snoRNA-associated protein 20; U three protein 20 |
Gene Name | UTP20 |
Gene Synonyms/Alias | YBL004W; YBL0101 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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516 | ASPDNFTKDMVGTLL | ubiquitination | [1] | 643 | RDLTIRIKNVGAEFG | ubiquitination | [1] |
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Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. |
Sequence Annotation | REPEAT 227 264 HEAT 1. REPEAT 495 532 HEAT 2. REPEAT 576 613 HEAT 3. REPEAT 845 882 HEAT 4. REPEAT 1176 1214 HEAT 5. REPEAT 1216 1252 HEAT 6. REPEAT 1342 1380 HEAT 7. REPEAT 1393 1430 HEAT 8. REPEAT 1480 1520 HEAT 9. REPEAT 1522 1558 HEAT 10. REPEAT 1588 1625 HEAT 11. REPEAT 1630 1667 HEAT 12. REPEAT 1890 1927 HEAT 13. REPEAT 1953 1992 HEAT 14. REPEAT 2120 2157 HEAT 15. REPEAT 2358 2397 HEAT 16. |
Keyword | Complete proteome; Cytoplasm; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2493 AA |
Protein Sequence | MAKQRQTTKS SKRYRYSSFK ARIDDLKIEP ARNLEKRVHD YVESSHFLAS FDQWKEINLS 60 AKFTEFAAEI EHDVQTLPQI LYHDKKIFNS LVSFINFHDE FSLQPLLDLL AQFCHDLGPD 120 FLKFYEEAIK TLINLLDAAI EFESSNVFEW GFNCLAYIFK YLSKFLVKKL VLTCDLLIPL 180 LSHSKEYLSR FSAEALSFLV RKCPVSNLRE FVRSVFEKLE GDDEQTNLYE GLLILFTESM 240 TSTQETLHSK AKAIMSVLLH EALTKSSPER SVSLLSDIWM NISKYASIES LLPVYEVMYQ 300 DFNDSLDATN IDRILKVLTT IVFSESGRKI PDWNKITILI ERIMSQSENC ASLSQDKVAF 360 LFALFIRNSD VKTLTLFHQK LFNYALTNIS DCFLEFFQFA LRLSYERVFS FNGLKFLQLF 420 LKKNWQSQGK KIALFFLEVD DKPELQKVRE VNFPEEFILS IRDFFVTAEI NDSNDLFEIY 480 WRAIIFKYSK LQNTEIIIPL LERIFSTFAS PDNFTKDMVG TLLKIYRKED DASGNNLLKT 540 ILDNYENYKE SLNFLRGWNK LVSNLHPSES LKGLMSHYPS LLLSLTDNFM LPDGKIRYET 600 LELMKTLMIL QGMQVPDLLS SCMVIEEIPL TLQNARDLTI RIKNVGAEFG KTKTDKLVSS 660 FFLKYLFGLL TVRFSPVWTG VFDTLPNVYT KDEALVWKLV LSFIKLPDEN QNLDYYQPLL 720 EDGANKVLWD SSVVRLRDTI DTFSHIWSKY STQNTSIIST TIERRGNTTY PILIRNQALK 780 VMLSIPQVAE NHFVDIAPFV YNDFKTYKDE EDMENERVIT GSWTEVDRNV FLKTLSKFKN 840 IKNVYSATEL HDHLMVLLGS RNTDVQKLAL DALLAYKNPT LNKYRDNLKN LLDDTLFKDE 900 ITTFLTENGS QSIKAEDEKV VMPYVLRIFF GRAQVPPTSG QKRSRKIAVI SVLPNFKKPY 960 INDFLSLASE RLDYNYFFGN SHQINSSKAT LKTIRRMTGF VNIVNSTLSV LRTNFPLHTN 1020 SVLQPLIYSI AMAYYVLDTE STEEVHLRKM ASNLRQQGLK CLSSVFEFVG NTFDWSTSME 1080 DIYAVVVKPR ISHFSDENLQ QPSSLLRLFL YWAHNPSLYQ FLYYDEFATA TALMDTISNQ 1140 HVKEAVIGPI IEAADSIIRN PVNDDHYVDL VTLICTSCLK ILPSLYVKLS DSNSISTFLN 1200 LLVSITEMGF IQDDHVRSRL ISSLISILKG KLKKLQENDT QKILKILKLI VFNYNCSWSD 1260 IEELYTTISS LFKTFDERNL RVSLTELFIE LGRKVPELES ISKLVADLNS YSSSRMHEYD 1320 FPRILSTFKG LIEDGYKSYS ELEWLPLLFT FLHFINNKEE LALRTNASHA IMKFIDFINE 1380 KPNLNEASKS ISMLKDILLP NIRIGLRDSL EEVQSEYVSV LSYMVKNTKY FTDFEDMAIL 1440 LYNGDEEADF FTNVNHIQLH RRQRAIKRLG EHAHQLKDNS ISHYLIPMIE HYVFSDDERY 1500 RNIGNETQIA IGGLAQHMSW NQYKALLRRY ISMLKTKPNQ MKQAVQLIVQ LSVPLRETLR 1560 IVRDGAESKL TLSKFPSNLD EPSNFIKQEL YPTLSKILGT RDDETIIERM PIAEALVNIV 1620 LGLTNDDITN FLPSILTNIC QVLRSKSEEL RDAVRVTLGK ISIILGAEYL VFVIKELMAT 1680 LKRGSQIHVL SYTVHYILKS MHGVLKHSDL DTSSSMIVKI IMENIFGFAG EEKDSENYHT 1740 KVKEIKSNKS YDAGEILASN ISLTEFGTLL SPVKALLMVR INLRNQNKLS ELLRRYLLGL 1800 NHNSDSESES ILKFCHQLFQ ESEMSNSPQI PKKKVKDQVD EKEDFFLVNL ESKSYTINSN 1860 SLLLNSTLQK FALDLLRNVI TRHRSFLTVS HLEGFIPFLR DSLLSENEGV VISTLRILIT 1920 LIRLDFSDES SEIFKNCARK VLNIIKVSPS TSSELCQMGL KFLSAFIRHT DSTLKDTALS 1980 YVLGRVLPDL NEPSRQGLAF NFLKALVSKH IMLPELYDIA DTTREIMVTN HSKEIRDVSR 2040 SVYYQFLMEY DQSKGRLEKQ FKFMVDNLQY PTESGRQSVM ELINLIITKA NPALLSKLSS 2100 SFFLALVNVS FNDDAPRCRE MASVLISTML PKLENKDLEI VEKYIAAWLK QVDNASFLNL 2160 GLRTYKVYLK SIGFEHTIEL DELAIKRIRY ILSDTSVGSE HQWDLVYSAL NTFSSYMEAT 2220 ESVYKHGFKD IWDGIITCLL YPHSWVRQSA ANLVHQLIAN KDKLEISLTN LEIQTIATRI 2280 LHQLGAPSIP ENLANVSIKT LVNISILWKE QRTPFIMDVS KQTGEDLKYT TAIDYMVTRI 2340 GGIIRSDEHR MDSFMSKKAC IQLLALLVQV LDEDEVIAEG EKILLPLYGY LETYYSRAVD 2400 EEQEELRTLS NECLKILEDK LQVSDFTKIY TAVKQTVLER RKERRSKRAI LAVNAPQISA 2460 DKKLRKHARS REKRKHEKDE NGYYQRRNKR KRA 2493 |
Gene Ontology | GO:0030686; C:90S preribosome; IDA:SGD. GO:0005737; C:cytoplasm; IDA:SGD. GO:0005730; C:nucleolus; IDA:SGD. GO:0005654; C:nucleoplasm; IDA:SGD. GO:0030688; C:preribosome, small subunit precursor; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. |
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