CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034656
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Latrophilin-1 
Protein Synonyms/Alias
  
Gene Name
 Lphn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1157MWNDTVRKQTESSFMubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113
Functional Description
  
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; G-protein coupled receptor; Membrane; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1470 AA 
Protein Sequence
MARLAAALWS LCVTTVLVTS ATQGLSRAGL PFGLMRRELA CEGYPIELRC PGSDVIMVEN 60
ANYGRTDDKI CDADPFQMEN VQCYLPDAFK IMSQRCNNRT QCVVVAGSDA FPDPCPGTYK 120
YLEVQYDCVP YKVEQKVFVC PGTLQKVLEP TSTHESEHQS GAWCKDPLQA GDRIYVMPWI 180
PYRTDTLTEY ASWEDYVAAR HTTTYRLPNR VDGTGFVVYD GAVFYNKERT RNIVKYDLRT 240
RIKSGETVIN TANYHDTSPY RWGGKTDIDL AVDENGLWVI YATEGNNGRL VVSQLNPYTL 300
RFEGTWETGY DKRSASNAFM VCGVLYVLRS VYVDDDSEAA GNRVDYAFNT NANREEPVSL 360
AFPNPYQFVS SVDYNPRDNQ LYVWNNYFVV RYSLEFGPPD PSAGPATSPP LSTTTTARPT 420
PLTSTASPAA TTPLRRAPLT THPVGAINQL GPDLPPATAP APSTRRPPAP NLHVSPELFC 480
EPREVRRVQW PATQQGMLVE RPCPKGTRGI ASFQCLPALG LWNPRGPDLS NCTSPWVNQV 540
AQKIKSGENA ANIASELARH TRGSIYAGDV SSSVKLMEQL LDILDAQLQA LRPIERESAG 600
KNYNKMHKRE RTCKDYIKAV VETVDNLLRP EALESWKDMN ATEQVHTATM LLDVLEEGAF 660
LLADNVREPA RFLAAKQNVV LEVTVLSTEG QVQELVFPQE YASESSIQLS ANTIKQNSRN 720
GVVKVVFILY NNLGLFLSTE NATVKLAGEA GTGGPGGASL VVNSQVIAAS INKESSRVFL 780
MDPVIFTVAH LEAKNHFNAN CSFWNYSERS MLGYWSTQGC RLVESNKTHT TCACSHLTNF 840
AVLMAHREIY QGRINELLLS VITWVGIVIS LVCLAICIST FCFLRGLQTD RNTIHKNLCI 900
NLFLAELLFL VGIDKTQYEV ACPIFAGLLH YFFLAAFSWL CLEGVHLYLL LVEVFESEYS 960
RTKYYYLGGY CFPALVVGIA AAIDYRSYGT EKACWLRVDN YFIWSFIGPV SFVIVVNLVF 1020
LMVTLHKMIR SSSVLKPDSS RLDNIKSWAL GAIALLFLLG LTWAFGLLFI NKESVVMAYL 1080
FTTFNAFQGV FIFVFHCALQ KKVHKEYSKC LRHSYCCIRS PPGGHGSLKT SAMRSNTRYY 1140
TGTQSRIRRM WNDTVRKQTE SSFMAGDINS TPTLNRGTMG NHLLTNPVLQ PRGGTSPYNT 1200
LIAESVGFNP SSPPVFNSPG SYREPKHPLG GREACGMDTL PLNGNFNNSY SLRSGDFPPG 1260
DGGPEPPRGR NLADAAAFEK MIISELVHNN LRGASGGAKG PPPEPPVPPV PGVSEDEAGG 1320
PGGADRAEIE LLYKALEEPL LLPRAQSVLY QSDLDESESC TAEDGATSRP LSSPPGRDSL 1380
YASGANLRDS PSYPDSSPEG PNEALPPPPP APPGPPEIYY TSRPPALVAR NPLQGYYQVR 1440
RPSHEGYLAA PSLEGPGPDG DGQMQLVTSL 1470 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
 GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. 
Interpro
 IPR022624; DUF3497.
 IPR017981; GPCR_2-like.
 IPR001879; GPCR_2_extracellular_dom.
 IPR003924; GPCR_2_latrophilin.
 IPR003334; GPCR_2_latrophilin_rcpt_C.
 IPR000832; GPCR_2_secretin-like.
 IPR017983; GPCR_2_secretin-like_CS.
 IPR000203; GPS_dom.
 IPR000922; Lectin_gal-bd_dom.
 IPR003112; Olfac-like. 
Pfam
 PF00002; 7tm_2
 PF12003; DUF3497
 PF02140; Gal_Lectin
 PF01825; GPS
 PF02793; HRM
 PF02354; Latrophilin
 PF02191; OLF 
SMART
 SM00303; GPS
 SM00008; HormR
 SM00284; OLF 
PROSITE
 PS00650; G_PROTEIN_RECEP_F2_2
 PS50227; G_PROTEIN_RECEP_F2_3
 PS50261; G_PROTEIN_RECEP_F2_4
 PS50221; GPS
 PS51132; OLF
 PS50228; SUEL_LECTIN 
PRINTS
 PR00249; GPCRSECRETIN.
 PR01444; LATROPHILIN.