UniProt Accession

 SILR_SALTM; Q9ZHD3 

Genbank Protein ID

 AF067954 

Genbank Nucleotide ID

 AAD11745.1 

Protein Name

 Probable transcriptional regulatory protein SilR 

Protein Synonyms/Alias

  

Gene Name

 silR 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium 

NCBI Taxa ID

 90371 

Lysine Modification

Position	Peptide	Type	References
203	AVKRLRAKIDNDYGT	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Component of the sil cation-efflux system that confers resistance to silver. Probable member of a two-component regulatory system SilS/SilR. 

Sequence Annotation

 DOMAIN 1 116 Response regulatory.
 MOD_RES 51 51 4-aspartylphosphate (By similarity).  

Keyword

 Cytoplasm; DNA-binding; Phosphoprotein; Plasmid; Transcription; Transcription regulation; Two-component regulatory system. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 228 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR011006; CheY-like_superfamily.
 IPR001867; Sig_transdc_resp-reg_C.
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR006291; Sig_transdc_resp-reg_metal.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00072; Response_reg
 PF00486; Trans_reg_C 

SMART

 SM00448; REC
 SM00862; Trans_reg_C 

PROSITE

 PS50110; RESPONSE_REGULATORY 

PRINTS