| Tag | Content |
|---|
| CPLM ID | CPLM-001978 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tubulin alpha-1A chain |
Protein Synonyms/Alias | Alpha-tubulin 1; Tubulin alpha-1 chain |
Gene Name | TUBA1A |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Sus scrofa (Pig) |
NCBI Taxa ID | 9823 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | DGQMPSDKTIGGGDD | acetylation | [1] |
|
Reference | [1] Expression pattern of acetylated alpha-tubulin in porcine spermatogonia. Luo J, Rodriguez-Sosa JR, Tang L, Bondareva A, Megee S, Dobrinski I. Mol Reprod Dev. 2010 Apr;77(4):348-52. [ PMID: 20043318] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Sequence Annotation | NP_BIND 142 148 GTP (Potential).
MOD_RES 6 6 Phosphoserine (By similarity).
MOD_RES 48 48 Phosphoserine (By similarity).
MOD_RES 83 83 Nitrated tyrosine (By similarity).
MOD_RES 282 282 Nitrated tyrosine (By similarity).
MOD_RES 319 319 Phosphotyrosine (By similarity).
MOD_RES 432 432 Phosphotyrosine (By similarity).
MOD_RES 439 439 Phosphoserine (By similarity). |
Keyword | 3D-structure; Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; GTP-binding; Microtubule; Nitration; Nucleotide-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 451 AA |
Protein Sequence | MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK 60
HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIIDLVLD 120
RIRKLADQCT GLQGFSVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA 180
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA 240
SLRFDGALNV DLTEFQTNLV PYPRAHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN 300
QMVKCDPRHG KYMACCLLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYEPP 360
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDMAALEK DYEEVGVDSV EGEGEEEGEE Y 451 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |