UniProt Accession

 STX7_RAT; O70257; Q5U337 

Genbank Protein ID

 AF031430; BC085737 

Genbank Nucleotide ID

 AAC17131.1; AAH85737.1 

Protein Name

 Syntaxin-7 

Protein Synonyms/Alias

  

Gene Name

 Stx7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
64	QYTNQLAKETDKYIK	ubiquitination	[1]

Reference

 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). 

Sequence Annotation

 DOMAIN 165 227 t-SNARE coiled-coil homology.
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 79 79 Phosphothreonine (By similarity).
 MOD_RES 125 125 Phosphoserine (By similarity).
 MOD_RES 126 126 Phosphoserine (By similarity).
 MOD_RES 129 129 Phosphoserine (By similarity).
 MOD_RES 205 205 Phosphoserine (By similarity).  

Keyword

 Acetylation; Coiled coil; Complete proteome; Endosome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 261 AA 

Protein Sequence

Gene Ontology

 GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031902; C:late endosome membrane; IDA:RGD.
 GO:0005765; C:lysosomal membrane; IDA:RGD.
 GO:0031201; C:SNARE complex; IDA:UniProtKB.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
 GO:0008333; P:endosome to lysosome transport; IDA:RGD.
 GO:0006886; P:intracellular protein transport; IBA:RefGenome.
 GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.
 GO:0006906; P:vesicle fusion; IDA:RGD. 

Interpro

 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 

Pfam

 PF05739; SNARE
 PF00804; Syntaxin 

SMART

 SM00503; SynN
 SM00397; t_SNARE 

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS