CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023374
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetratricopeptide repeat protein 14 homolog 
Protein Synonyms/Alias
 TPR repeat protein 14 homolog 
Gene Name
 CG6621 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
849RTVEPNGKDERAATPacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
 REPEAT 302 335 TPR 1.
 REPEAT 336 369 TPR 2.
 REPEAT 377 410 TPR 3.
 MOD_RES 536 536 Phosphoserine.
 MOD_RES 538 538 Phosphothreonine.
 MOD_RES 540 540 Phosphoserine.
 MOD_RES 606 606 Phosphoserine.
 MOD_RES 607 607 Phosphoserine.
 MOD_RES 769 769 Phosphoserine.
 MOD_RES 771 771 Phosphoserine.
 MOD_RES 778 778 Phosphoserine.
 MOD_RES 780 780 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 872 AA 
Protein Sequence
MNFDYIGQAL GYHGQPLQKI WDDERGVDDL RLMGLTQVNY GVYQERQKYF TFQERAKRLK 60
MHQFLARKAT DLYDRTLVAN VMEDSLLAQG NTYMTQMAPF EFFLNVKDKR KGWAHRLSAL 120
KQGDIIYTQV TRLASGNRLI VKPLCTAEPK HAYLADIPIK AVILQDFWGP LPLDKQGNPR 180
SFVQNDILRC EINNISADTE RLSLNMIGMF NKVPDLKFGL CDFKELPKYY SKIHNLDHPS 240
ASHYEDELNK ALEFENPNYD LLFQMNGLQP NENLSLMSYL RAGFPEEENA AELRQKQASQ 300
WAFRSVADGI EHFKNGQQVE AFQCLNKALN IDPRNVEALV ARGALYANRG SFLKGLQDFE 360
KALHLNKYHV NARKYMGETL VALGRSYEEE NRIAEAVKAY SDCLNLLPLH EEARQSLDAL 420
HRSGDGKRRI STEPSNMTGG QSSDESSSSS ASDSECEDSA GKPKSNISQP FYAQHKLKQS 480
GDEKLAVIDA HKANEFRLDD DETVSSVRKL LREASKHKKA KKKGKKKKDK KERRRSRTKS 540
ETEDPIELLK KIDFQEALRQ DNKLMNSTRS DEERKAKIKS YLKEGGKESP PPPPPMKKTA 600
VSSRKSSFDN VGPSTSRHAA SVVGFGGAQP PPAPKFLGQK KHPEPAPKLS FQIKKRPLQM 660
DKLGMLRLAA PAEPLKGGRS SSSRSRSRSR SRSRSRSRNR RLGRSTRSSL RSRRSGSRSR 720
SISRSRSRRR RTYSRSRSPS PRSYGNRFVI GRYRNRRTRR SRSFHRRRSP SPILKRRSPS 780
PFVPRRTPSP ASRYRRSRSR SRSRSRSRSP RRFQSRYMPR DRGSVNRSRY SWHNPHKRSV 840
SRTVEPNGKD ERAATPPKKG VADDRSGREE RA 872 
Gene Ontology
  
Interpro
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2.
 IPR019734; TPR_repeat. 
Pfam
 PF07719; TPR_2 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS