CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Catenin beta-1 
Protein Synonyms/Alias
  
Gene Name
 Ctnnb1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
19MAMEPDRKAAVSHWQubiquitination[1]
133AEPSQMLKHAVVNLIubiquitination[1]
158RAIPELTKLLNDEDQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 174 AA 
Protein Sequence
MATQADLMEL DMAMEPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG NPEEEDVDTS 60
QVLYEWEQGF SQSFTQEQVA DIDGQYAMTR AQRVRAAMFP ETLDEGMQIP STQFDAAHPT 120
NVQRLAEPSQ MLKHAVVNLI NYQDDAELAT RAIPELTKLL NDEDQVVVNK AAVM 174 
Gene Ontology
 GO:0045177; C:apical part of cell; IDA:MGI.
 GO:0016323; C:basolateral plasma membrane; IDA:MGI.
 GO:0030877; C:beta-catenin destruction complex; IDA:MGI.
 GO:0070369; C:beta-catenin-TCF7L2 complex; IEA:Compara.
 GO:0016342; C:catenin complex; IBA:RefGenome.
 GO:0005938; C:cell cortex; IEA:Compara.
 GO:0005924; C:cell-substrate adherens junction; IEA:Compara.
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0043198; C:dendritic shaft; IBA:RefGenome.
 GO:0030057; C:desmosome; IBA:RefGenome.
 GO:0005916; C:fascia adherens; IDA:MGI.
 GO:0009898; C:internal side of plasma membrane; IBA:RefGenome.
 GO:0030027; C:lamellipodium; IDA:MGI.
 GO:0016328; C:lateral plasma membrane; IDA:MGI.
 GO:0031528; C:microvillus membrane; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0032993; C:protein-DNA complex; IEA:Compara.
 GO:0045202; C:synapse; IBA:RefGenome.
 GO:0005667; C:transcription factor complex; IDA:MGI.
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0005915; C:zonula adherens; IBA:RefGenome.
 GO:0045294; F:alpha-catenin binding; IDA:MGI.
 GO:0045296; F:cadherin binding; ISO:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003690; F:double-stranded DNA binding; IDA:MGI.
 GO:0019901; F:protein kinase binding; IBA:RefGenome.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
 GO:0005198; F:structural molecule activity; IBA:RefGenome.
 GO:0003713; F:transcription coactivator activity; IDA:MGI.
 GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
 GO:0034333; P:adherens junction assembly; IEA:Compara.
 GO:0009948; P:anterior/posterior axis specification; IMP:MGI.
 GO:0006915; P:apoptotic process; IMP:MGI.
 GO:0045453; P:bone resorption; IMP:MGI.
 GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:MGI.
 GO:0044336; P:canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process; IEA:Compara.
 GO:0044334; P:canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition; IEA:Compara.
 GO:0001708; P:cell fate specification; IMP:MGI.
 GO:0048469; P:cell maturation; IDA:MGI.
 GO:0016337; P:cell-cell adhesion; IMP:MGI.
 GO:0007160; P:cell-matrix adhesion; IMP:MGI.
 GO:0071363; P:cellular response to growth factor stimulus; IEA:Compara.
 GO:0071681; P:cellular response to indole-3-methanol; IEA:Compara.
 GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
 GO:0022009; P:central nervous system vasculogenesis; IMP:MGI.
 GO:0007016; P:cytoskeletal anchoring at plasma membrane; IBA:RefGenome.
 GO:0009950; P:dorsal/ventral axis specification; IMP:MGI.
 GO:0007398; P:ectoderm development; IMP:MGI.
 GO:0000578; P:embryonic axis specification; IDA:MGI.
 GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.
 GO:0048617; P:embryonic foregut morphogenesis; IMP:MGI.
 GO:0035115; P:embryonic forelimb morphogenesis; IDA:MGI.
 GO:0035050; P:embryonic heart tube development; IMP:MGI.
 GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.
 GO:0001711; P:endodermal cell fate commitment; IMP:MGI.
 GO:0061154; P:endothelial tube morphogenesis; IEA:Compara.
 GO:0060742; P:epithelial cell differentiation involved in prostate gland development; IMP:MGI.
 GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IMP:MGI.
 GO:0030900; P:forebrain development; IMP:MGI.
 GO:0061198; P:fungiform papilla formation; IMP:MGI.
 GO:0001702; P:gastrulation with mouth forming second; IMP:MGI.
 GO:0035112; P:genitalia morphogenesis; IMP:MGI.
 GO:0007403; P:glial cell fate determination; IDA:MGI.
 GO:0031069; P:hair follicle morphogenesis; IMP:MGI.
 GO:0060789; P:hair follicle placode formation; IMP:MGI.
 GO:0030902; P:hindbrain development; IBA:RefGenome.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0002089; P:lens morphogenesis in camera-type eye; IMP:MGI.
 GO:0001889; P:liver development; IBA:RefGenome.
 GO:0060479; P:lung cell differentiation; IMP:MGI.
 GO:0060492; P:lung induction; IMP:MGI.
 GO:0060484; P:lung-associated mesenchyme development; IMP:MGI.
 GO:0030539; P:male genitalia development; IMP:MGI.
 GO:0060916; P:mesenchymal cell proliferation involved in lung development; IMP:MGI.
 GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IDA:MGI.
 GO:0007494; P:midgut development; IEA:Compara.
 GO:0045445; P:myoblast differentiation; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0032331; P:negative regulation of chondrocyte differentiation; IGI:MGI.
 GO:0003136; P:negative regulation of heart induction by canonical Wnt receptor signaling pathway; IBA:RefGenome.
 GO:0048715; P:negative regulation of oligodendrocyte differentiation; IMP:MGI.
 GO:0045671; P:negative regulation of osteoclast differentiation; IMP:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0072079; P:nephron tubule formation; IMP:MGI.
 GO:0001840; P:neural plate development; IDA:MGI.
 GO:0001764; P:neuron migration; IGI:MGI.
 GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.
 GO:0048599; P:oocyte development; IGI:MGI.
 GO:0030316; P:osteoclast differentiation; IMP:MGI.
 GO:0060066; P:oviduct development; IMP:MGI.
 GO:0031016; P:pancreas development; IMP:MGI.
 GO:0001569; P:patterning of blood vessels; IMP:MGI.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0061047; P:positive regulation of branching involved in lung morphogenesis; IMP:MGI.
 GO:2000017; P:positive regulation of determination of dorsal identity; IDA:MGI.
 GO:0045603; P:positive regulation of endothelial cell differentiation; IMP:MGI.
 GO:0060769; P:positive regulation of epithelial cell proliferation involved in prostate gland development; IMP:MGI.
 GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IMP:MGI.
 GO:0010909; P:positive regulation of heparan sulfate proteoglycan biosynthetic process; IEA:Compara.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.
 GO:0043410; P:positive regulation of MAPK cascade; IGI:MGI.
 GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.
 GO:0002052; P:positive regulation of neuroblast proliferation; IGI:MGI.
 GO:0045669; P:positive regulation of osteoblast differentiation; IMP:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0051291; P:protein heterooligomerization; IEA:Compara.
 GO:0034394; P:protein localization to cell surface; IEA:Compara.
 GO:0009954; P:proximal/distal pattern formation; IMP:MGI.
 GO:0090279; P:regulation of calcium ion import; IEA:Compara.
 GO:0030997; P:regulation of centriole-centriole cohesion; IEA:Compara.
 GO:0031641; P:regulation of myelination; IMP:MGI.
 GO:2000008; P:regulation of protein localization to cell surface; IEA:Compara.
 GO:0003266; P:regulation of secondary heart field cardioblast proliferation; IDA:MGI.
 GO:0048660; P:regulation of smooth muscle cell proliferation; IEA:Compara.
 GO:0042129; P:regulation of T cell proliferation; IMP:MGI.
 GO:0072053; P:renal inner medulla development; IMP:MGI.
 GO:0072054; P:renal outer medulla development; IMP:MGI.
 GO:0072033; P:renal vesicle formation; IMP:MGI.
 GO:0046686; P:response to cadmium ion; IEA:Compara.
 GO:0034097; P:response to cytokine stimulus; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0032355; P:response to estradiol stimulus; IEA:Compara.
 GO:0043627; P:response to estrogen stimulus; IBA:RefGenome.
 GO:0014010; P:Schwann cell proliferation; IBA:RefGenome.
 GO:0001501; P:skeletal system development; IMP:MGI.
 GO:0043588; P:skin development; IMP:MGI.
 GO:0051145; P:smooth muscle cell differentiation; IMP:MGI.
 GO:0050808; P:synapse organization; IMP:MGI.
 GO:0048489; P:synaptic vesicle transport; IMP:MGI.
 GO:0033077; P:T cell differentiation in thymus; IMP:MGI.
 GO:0048538; P:thymus development; IMP:MGI.
 GO:0060440; P:trachea formation; IMP:MGI. 
Interpro
 IPR013284; Beta-catenin. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR01869; BCATNINFAMLY.