UniProt Accession

 E9QPX3_MOUSE; E9QPX3 

Genbank Protein ID

 CT010486 

Genbank Nucleotide ID

  

Protein Name

 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Ndufs4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
73	GVPEEHIKTRKVRIF	ubiquitination	[1]
150	WSYDVEEKKVPKPKS	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 175 AA 

Protein Sequence

Gene Ontology

 GO:0005747; C:mitochondrial respiratory chain complex I; IDA:MGI.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:MGI.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0019933; P:cAMP-mediated signaling; IEA:Compara.
 GO:0045333; P:cellular respiration; IEA:Compara.
 GO:0022900; P:electron transport chain; IEA:InterPro.
 GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Compara.
 GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Compara.
 GO:0072593; P:reactive oxygen species metabolic process; IEA:Compara.
 GO:0001932; P:regulation of protein phosphorylation; ISO:MGI.
 GO:0051591; P:response to cAMP; IEA:Compara. 

Interpro

 IPR006885; NADH_UbQ_FeS_4_mit. 

Pfam

 PF04800; ETC_C1_NDUFA4 

SMART

  

PROSITE

  

PRINTS