| Tag | Content |
|---|
| CPLM ID | CPLM-017734 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Exonuclease 3'-5' domain-containing protein 1 |
Protein Synonyms/Alias | Exonuclease 3'-5' domain-like-containing protein 1 |
Gene Name | EXD1 |
Gene Synonyms/Alias | EXDL1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 224 | KYLSFLEKRQKLIQE | ubiquitination | [1] |
|
Reference | [1] Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Xu G, Paige JS, Jaffrey SR. Nat Biotechnol. 2010 Aug;28(8):868-73. [ PMID: 20639865] |
Functional Description | |
Sequence Annotation | DOMAIN 30 122 3'-5' exonuclease. |
Keyword | Alternative splicing; Complete proteome; Exonuclease; Hydrolase; Nuclease; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 514 AA |
Protein Sequence | MEDSEFLAYV ELLDEVEQGS VRAKASSVSL HAERTWMEKM KVEDLNVCEP ASPAPEAPAT 60
SLLNDLKYSP SEEEEVTYTV INQFQQKFGA AILHIKKQNV LSVAAEGANV CRHGKLCWLQ 120
VATNCRVYLF DIFLLGSRAF HNGLQMILED KRILKVIHDC RWLSDCLSHQ YGILLNNVFD 180
TQVADVLQFS METGGYLPNC ITTLQESLIK HLQVAPKYLS FLEKRQKLIQ ENPEVWFIRP 240
VSPSLLKILA LEATYLLPLR LALLDEMMSD LTTLVDGYLN TYREGSADRL GGTEPTCMEL 300
PEELLQLKDF QKQRREKAAR EYRVNAQGLL IRTVLQPKKL VTETAGKEEK VKGFLFGKNF 360
RIDKAPSFTS QDFHGDVNLL KEESLNKQAT NPQHLPPTEE GETSEDSSNK LICTKSKGSE 420
DQRITQKEHF MTPKHEFQAS LSLKEETEQL LMVENKEDLK CTKQAVSMSS FPQETRVSPS 480
DTFYPIRKTV VSTLPPCPAL EKIDSWISPF LNLP 514 |
Gene Ontology | GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |