CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glyceraldehyde-3-phosphate dehydrogenase 2 
Protein Synonyms/Alias
 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH 
Gene Name
 gapB 
Gene Synonyms/Alias
 BSU29020 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
56TIHGRYDKEVVAGEDacetylation[1]
70DSLIVNGKKVLLLNSacetylation[1]
193KNIDNPHKDLRRARAacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
 More active in anabolism. 
Sequence Annotation
 NP_BIND 12 13 NAD (By similarity).
 REGION 151 153 Glyceraldehyde 3-phosphate binding (By
 REGION 210 211 Glyceraldehyde 3-phosphate binding (By
 ACT_SITE 152 152 Nucleophile (By similarity).
 BINDING 78 78 NAD; via carbonyl oxygen (By similarity).
 BINDING 182 182 Glyceraldehyde 3-phosphate (By
 BINDING 197 197 Glyceraldehyde 3-phosphate (By
 BINDING 233 233 Glyceraldehyde 3-phosphate (By
 BINDING 315 315 NAD (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Glycolysis; NAD; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
MKVKVAINGF GRIGRMVFRK AMLDDQIQVV AINASYSAET LAHLIKYDTI HGRYDKEVVA 60
GEDSLIVNGK KVLLLNSRDP KQLPWREYDI DIVVEATGKF NAKDKAMGHI EAGAKKVILT 120
APGKNEDVTI VMGVNEDQFD AERHVIISNA SCTTNCLAPV VKVLDEEFGI ESGLMTTVHA 180
YTNDQKNIDN PHKDLRRARA CGESIIPTTT GAAKALSLVL PHLKGKLHGL ALRVPVPNVS 240
LVDLVVDLKT DVTAEEVNEA FKRAAKTSMY GVLDYSDEPL VSTDYNTNPH SAVIDGLTTM 300
VMEDRKVKVL AWYDNEWGYS CRVVDLIRHV AARMKHPSAV 340 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0043891; F:glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity; IEA:EC.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 
SMART
 SM00846; Gp_dh_N 
PROSITE
 PS00071; GAPDH 
PRINTS
 PR00078; G3PDHDRGNASE.