| Tag | Content |
|---|
| CPLM ID | CPLM-020013 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Long-chain-fatty-acid--CoA ligase ACSBG1 |
Protein Synonyms/Alias | Acyl-CoA synthetase bubblegum family member 1; mBG1; Gonadotropin-regulated long chain acyl CoA synthetase; GR-LACS; Lipidosin |
Gene Name | Acsbg1 |
Gene Synonyms/Alias | Kiaa0631; Lpd |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 65 | LELSAPEKARAASLD | ubiquitination | [1] | | 211 | VIVVDTQKQLEKILK | ubiquitination | [1] | | 378 | GVPRVWEKIMERIQE | ubiquitination | [1] | | 639 | FCQRVGSKASTVSEI | ubiquitination | [1] | | 698 | GELGPTMKLKRLTVL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids (By similarity). |
Sequence Annotation | NP_BIND 279 287 ATP (By similarity).
NP_BIND 469 474 ATP (By similarity).
BINDING 547 547 ATP (By similarity).
BINDING 562 562 ATP (By similarity).
BINDING 698 698 ATP (By similarity).
MOD_RES 655 655 Phosphotyrosine. |
Keyword | ATP-binding; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Endoplasmic reticulum; Fatty acid metabolism; Ligase; Lipid metabolism; Microsome; Nucleotide-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 721 AA |
Protein Sequence | MPRGSEAGYC CLSRDSNMPD SRDDQQQGAS LGTSQDNSQT SSLIDGQTLS KESPSHGLEL 60
SAPEKARAAS LDGAEEALWT TRADGRVRLR LEPFCTQRPY TVHQMFYEAL DKYGNLSALG 120
FKRKDKWERI SYYQYYLIAR KVAKGFLKLG LERAHSVAIL GFNSPEWFFS AVGTVFAGGI 180
VTGIYTTSSP EACQYISHDC RANVIVVDTQ KQLEKILKIW KDLPHLKAVV IYQEPPPKKM 240
ANVYTMEELI ELGQEVPEEA LDAIIDTQQP NQCCVLVYTS GTTGNPKGVM LSQDNITWTA 300
RYGSQAGDIQ PAEVQQEVVV SYLPLSHIAA QIYDLWTGIQ WGAQVCFADP DALKGTLVNT 360
LREVEPTSHM GVPRVWEKIM ERIQEVAAQS GFIRRKMLLW AMSVTLEQNL TCPSNDLKPF 420
TSRLADYLVL ARVRQALGFA KCQKNFYGAA PMTAETQRFF LGLNIRLYAG YGLSESTGPH 480
FMSSPYNYRL YSSGRVVPGC RVKLVNQDAD GIGEICLWGR TIFMGYLNME DKTCEAIDSE 540
GWLHTGDMGR LDADGFLYIT GRLKELIITA GGENVPPVPI EEAVKMELPI ISSAMLIGDQ 600
RKFLSMLLTL KCTLDPETSE PTDSLTEQAV EFCQRVGSKA STVSEIVGQR DEAVYQAIHE 660
GIQRVNANAA ARPYHIQKWA ILQRDFSISG GELGPTMKLK RLTVLEKYKD IIDSFYQEQK 720
Q 721 |
Gene Ontology | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004467; F:long-chain fatty acid-CoA ligase activity; ISS:HGNC. GO:0031957; F:very long-chain fatty acid-CoA ligase activity; ISS:HGNC. GO:0001552; P:ovarian follicle atresia; IEA:Compara. GO:0051384; P:response to glucocorticoid stimulus; IMP:MGI. GO:0000038; P:very long-chain fatty acid metabolic process; ISS:HGNC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |