CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008555
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable alanine aminotransferase 
Protein Synonyms/Alias
 Glutamate pyruvate transaminase; GPT; Glutamic--alanine transaminase; Glutamic--pyruvic transaminase 
Gene Name
 ALT2 
Gene Synonyms/Alias
 YDR111C; YD9727.07C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
37DLNTGVTKAEYAVRGubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 MOD_RES 327 327 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Aminotransferase; Complete proteome; Cytoplasm; Nucleus; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MTMTHQQDLK GVFTAKDLDF KPAGKITKKD LNTGVTKAEY AVRGAIPTRA DELKEELKKN 60
PEVLPFDDII NANIGNPQQL DQKPLTFTRQ VLAILEYPEI LRVGHNELAS LNLFSRDALE 120
RAERLLNDIG GSIGAYSHSQ GVPGIRQTVA DFITRRDGGE PATPEDIYLT TGASSAATSL 180
LSLLCKDSQT GLLIPIPQYP LYTASASLFN AQVLPYYLDE ESNWSTNSDE IEKVVQDALK 240
KQIRPSVLIV INPGNPTGAV LSEETIARIC LIAAKYGITI ISDEVYQENI FNDVKFHSMK 300
KVLRKLQHLY PGKFDNVQLA SLHSISKGFM DECGQRGGYM EIIGFSQEIR DALFKLMSIS 360
ICSVVTGQAV VDLMVKPPQP GDESYEQDHD ERLKIFHEMR TRANLLYETF KELEGIECQK 420
PQGAMYLFPR LVLPKKALCE SERLGIEPDE FYCTSLLEST GICTVPGSGF GQRPGTYHVR 480
TTFLAPGTKW IQDWKEFHQD FFSKYRN 507 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008483; F:transaminase activity; ISS:SGD.
 GO:0009058; P:biosynthetic process; IEA:InterPro.
 GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
  
PRINTS