CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029956
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 
Protein Synonyms/Alias
  
Gene Name
 Atp2a3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
158VEVAVGDKVPADLRLubiquitination[1]
481VIKQLMRKEFTLEFSubiquitination[1]
695NDAPALKKAEIGIAMubiquitination[1]
740RAIYNNMKQFIRYLIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 981 AA 
Protein Sequence
MEEAHLLSAA DVLRRFSVTA EGGLSLEQVT DARERYGPNE LPTEEGKSLW ELVVEQFEDL 60
LVRILLLAAL VSFVLAWFEE GEETTTAFVE PLVIMLILVA NAIVGVWQER NAESAIEALK 120
EYEPEMGKVI RSDRKGVQRI RARDIVPGDI VEVAVGDKVP ADLRLIEIKS TTLRVDQSIL 180
TGESVSVTKH TDAIPDPRAV NQDKKNMLFS GTNIASGKAL GVAVATGLQT ELGKIRSQMA 240
AVEPERTPLQ RKLDEFGRQL SHAISVICVA VWVINIGHFA DPAHGGSWLR GAVYYFKIAV 300
ALAVAAIPEG LPAVITTCLA LGTRRMARKN AIVRSLPSVE TLGCTSVICS DKTGTLTTNQ 360
MSVCRMFVVA EAEAGTCRLH EFTISGTTYT PEGEVRQGEQ PVRCGQFDGL VELATICALC 420
NDSALDYNEA KGVYEKVGEA TETALTCLVE KMNVFDTDLK GLSRVERAGA CNSVIKQLMR 480
KEFTLEFSRD RKSMSVYCTP TRADPKVQGS KMFVKGAPES VIERCSSVRV GSRTAPLSTT 540
SREHILAKIR DWGSGSDTLR CLALATRDTP PRKEDMHLDD CSRFVQYEVA ACITRCSRAG 600
IRVVMITGDN KGTAVAICRR LGIFGDTEDV LGKAYTGREF DDLSPEQQRQ ACRTARCFAR 660
VEPAHKSRIV ENLQSFNEIT AMTGDGVNDA PALKKAEIGI AMGSGTAVAK SAAEMVLSDD 720
NFASIVAAVE EGRAIYNNMK QFIRYLISSN VGEVVCIFLT AILGLPEALI PVQLLWVNLV 780
TDGLPATALG FNPPDLDIME KPPRNPREAL ISGWLFFRYL AIGVYVGLAT VAAATWWFLY 840
DTEGPQVTFY QLRNFLKCSE DNPLFAGIDC KVFESRFPTT MALSVLVTIE MCNALNSVSE 900
NQSLLRMPPW LNPWLLGAVV MSMALHFLIL LVPPLPLIFQ VTPLSGRQWG VVLQMSLPVI 960
LLDEALKYLS RNHMDEKKDL K 981 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR005782; ATPase_P-typ_Ca-transp_IIA.
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF00702; Hydrolase 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.