UniProt Accession

 AP1S1_YEAST; P35181; D6VYH5 

Genbank Protein ID

 X70279; Z30314; U17246; AY692851; BK006945 

Genbank Nucleotide ID

 CAA49765.1; CAA82959.2; AAB67468.1; AAT92870.1; DAA09491.1 

Protein Name

 AP-1 complex subunit sigma-1 

Protein Synonyms/Alias

 Clathrin assembly protein complex 1 small chain; Clathrin coat assembly protein AP19; Clathrin coat-associated protein AP19; Golgi adaptor AP-1 19 kDa adaptin; HA1 19 kDa subunit; Sigma1-adaptin 

Gene Name

 APS1 

Gene Synonyms/Alias

 YAP19; YLR170C; L9470.16 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
35	GEKAKIVKDLTPTIL	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP19 is probably a subunit of the Golgi membrane adaptor. 

Sequence Annotation

  

Keyword

 Coated pit; Complete proteome; Cytoplasmic vesicle; Golgi apparatus; Membrane; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 156 AA 

Protein Sequence

Gene Ontology

 GO:0030121; C:AP-1 adaptor complex; IPI:SGD.
 GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.
 GO:0030276; F:clathrin binding; ISS:SGD.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006896; P:Golgi to vacuole transport; IMP:SGD.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 

Interpro

 IPR016635; AP_complex_ssu.
 IPR022775; AP_mu_sigma_su.
 IPR000804; Clathrin_sm-chain_CS.
 IPR011012; Longin-like_dom. 

Pfam

 PF01217; Clat_adaptor_s 

SMART

  

PROSITE

 PS00989; CLAT_ADAPTOR_S 

PRINTS