Tag | Content |
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CPLM ID | CPLM-009914 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Galactitol permease IIC component |
Protein Synonyms/Alias | EIIC-Gat; PTS system galactitol-specific EIIC component |
Gene Name | gatC |
Gene Synonyms/Alias | b2092; JW2076 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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208 | IPGVNRIKFSADDIQ | acetylation | [1] | 265 | LLMPRVIKPIMDGLT | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport. |
Sequence Annotation | DOMAIN 6 435 PTS EIIC type-2. |
Keyword | Cell inner membrane; Cell membrane; Complete proteome; Galactitol metabolism; Membrane; Phosphotransferase system; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 451 AA |
Protein Sequence | MFSEVMRYIL DLGPTVMLPI VIIIFSKILG MKAGDCFKAG LHIGIGFVGI GLVIGLMLDS 60 IGPAAKAMAE NFDLNLHVVD VGWPGSSPMT WASQIALVAI PIAILVNVAM LLTRMTRVVN 120 VDIWNIWHMT FTGALLHLAT GSWMIGMAGV VIHAAFVYKL GDWFARDTRN FFELEGIAIP 180 HGTSAYMGPI AVLVDAIIEK IPGVNRIKFS ADDIQRKFGP FGEPVTVGFV MGLIIGILAG 240 YDVKGVLQLA VKTAAVMLLM PRVIKPIMDG LTPIAKQARS RLQAKFGGQE FLIGLDPALL 300 LGHTAVVSAS LIFIPLTILI AVCVPGNQVL PFGDLATIGF FVAMAVAVHR GNLFRTLISG 360 VIIMSITLWI ATQTIGLHTQ LAANAGALKA GGMVASMDQG GSPITWLLIQ VFSPQNIPGF 420 IIIGAIYLTG IFMTWRRARG FIKQEKVVLA E 451 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015577; F:galactitol transmembrane transporter activity; IEA:InterPro. GO:0019402; P:galactitol metabolic process; IEA:UniProtKB-KW. GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. |
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PROSITE | |
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