CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009914
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Galactitol permease IIC component 
Protein Synonyms/Alias
 EIIC-Gat; PTS system galactitol-specific EIIC component 
Gene Name
 gatC 
Gene Synonyms/Alias
 b2092; JW2076 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
208IPGVNRIKFSADDIQacetylation[1]
265LLMPRVIKPIMDGLTacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in galactitol transport. 
Sequence Annotation
 DOMAIN 6 435 PTS EIIC type-2.  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Galactitol metabolism; Membrane; Phosphotransferase system; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 451 AA 
Protein Sequence
MFSEVMRYIL DLGPTVMLPI VIIIFSKILG MKAGDCFKAG LHIGIGFVGI GLVIGLMLDS 60
IGPAAKAMAE NFDLNLHVVD VGWPGSSPMT WASQIALVAI PIAILVNVAM LLTRMTRVVN 120
VDIWNIWHMT FTGALLHLAT GSWMIGMAGV VIHAAFVYKL GDWFARDTRN FFELEGIAIP 180
HGTSAYMGPI AVLVDAIIEK IPGVNRIKFS ADDIQRKFGP FGEPVTVGFV MGLIIGILAG 240
YDVKGVLQLA VKTAAVMLLM PRVIKPIMDG LTPIAKQARS RLQAKFGGQE FLIGLDPALL 300
LGHTAVVSAS LIFIPLTILI AVCVPGNQVL PFGDLATIGF FVAMAVAVHR GNLFRTLISG 360
VIIMSITLWI ATQTIGLHTQ LAANAGALKA GGMVASMDQG GSPITWLLIQ VFSPQNIPGF 420
IIIGAIYLTG IFMTWRRARG FIKQEKVVLA E 451 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0015577; F:galactitol transmembrane transporter activity; IEA:InterPro.
 GO:0019402; P:galactitol metabolic process; IEA:UniProtKB-KW.
 GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. 
Interpro
 IPR013853; GatC.
 IPR013014; PTS_EIIC_2.
 IPR004703; PTS_sugar-sp_permease. 
Pfam
 PF03611; EIIC-GAT 
SMART
  
PROSITE
 PS51104; PTS_EIIC_TYPE_2 
PRINTS