| Tag | Content |
|---|
| CPLM ID | CPLM-003436 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ |
Protein Synonyms/Alias | tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase; tRNA Cm32/Um32 methyltransferase |
Gene Name | trmJ |
Gene Synonyms/Alias | yfhQ; b2532; JW2516 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 211 | HPGQVMNKLRRLFTR | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. |
Sequence Annotation | BINDING 114 114 S-adenosyl-L-methionine; via carbonyl
BINDING 134 134 S-adenosyl-L-methionine; via amide
BINDING 143 143 S-adenosyl-L-methionine; via amide |
Keyword | Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine; Transferase; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 246 AA |
Protein Sequence | MLQNIRIVLV ETSHTGNMGS VARAMKTMGL TNLWLVNPLV KPDSQAIALA AGASDVIGNA 60
HIVDTLDEAL AGCSLVVGTS ARSRTLPWPM LDPRECGLKS VAEAANTPVA LVFGRERVGL 120
TNEELQKCHY HVAIAANPEY SSLNLAMAVQ VIAYEVRMAW LATQENGEQV EHEETPYPLV 180
DDLERFYGHL EQTLLATGFI RENHPGQVMN KLRRLFTRAR PESQELNILR GILASIEQQN 240
KGNKAE 246 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0003723; F:RNA binding; IEA:InterPro. GO:0016427; F:tRNA (cytosine) methyltransferase activity; IDA:EcoCyc. GO:0016300; F:tRNA (uracil) methyltransferase activity; IDA:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |