CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041557
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Copa 
Protein Synonyms/Alias
 RCG20221, isoform CRA_b 
Gene Name
 Copa 
Gene Synonyms/Alias
 rCG_20221 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
198GTTDAVVKHVLEGHDacetylation[1]
271ILSNSEDKSIRVWDMacetylation[1]
271ILSNSEDKSIRVWDMubiquitination[2]
280IRVWDMSKRTGVQTFacetylation[1]
337GNMLHYVKDRFLRQLacetylation[1]
441SLLIKNLKNEITKKIacetylation[1]
446NLKNEITKKIQVPNCacetylation[1]
480TLFDVQQKRTLASVKacetylation[1]
598TIDPTEFKFKLALINacetylation[1]
607KLALINRKYDEVLHMacetylation[1]
718GNLEKLRKMMKIAEIacetylation[1]
721EKLRKMMKIAEIRKDacetylation[1]
825FEGSIASKGKGGALAubiquitination[2]
1082KETLDQQKRICEMAAacetylation[1]
1134RLLELGPKPEVAQQTacetylation[1]
1211TTVTEIGKDVIGLRIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1224 AA 
Protein Sequence
MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH 60
KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF FHHEYPWILS ASDDQTIRVW 120
NWQSRTCVCV LTGHNHYVMC AQFHPSEDLV VSASLDQTVR VWDISGLRKK NLSPGAVESD 180
VRGITGVDLF GTTDAVVKHV LEGHDRGVNW AAFHPTMPLI VSGADDRQVK IWRMNESKAW 240
EVDTCRGHYN NVSCAVFHPR QELILSNSED KSIRVWDMSK RTGVQTFRRD HDRFWVLAAH 300
PNLNLFAAGH DGGMIVFKLE RERPAYAVHG NMLHYVKDRF LRQLDFNSSK DVAVMQLRSG 360
SKFPVFNMSY NPAENAVLLC TRASNLENST YDLYTIPKDA DSQNPDAPEG KRSSGLTAVW 420
VARNRFAVLD RMHSLLIKNL KNEITKKIQV PNCDEIFYAG TGNLLLRDAD SITLFDVQQK 480
RTLASVKISK VKYVIWSADM SHVALLAKHA IVICNRKLDA LCNIHENIRV KSGAWDESGV 540
FIYTTSNHIK YAVTTGDHGI IRTLDLPIYV TRVKGNNVYC LDRECRPRVL TIDPTEFKFK 600
LALINRKYDE VLHMVRNAKL VGQSIIAYLQ KKGYPEVALH FVKDEKTRFS LALECGNIEI 660
ALEAAKALDD KNCWEKLGEV ALLQGNHQIV EMCYQRTKNF DKLSFLYLIT GNLEKLRKMM 720
KIAEIRKDMS GHYQNALYLG DVSERVRILK NCGQKSLAYL TAATHGLDEE AESLKETFDP 780
EKETIPDIDP NAKLLQPPAP IMPLDTNWPL LTVSKGFFEG SIASKGKGGA LAADIDIDTV 840
GTEGWGEDAE LQLDEDGFVE APEGLGEDTL GKGQEEGGGW DVEEDLELPP ELDVPSGVAG 900
GAEDGFFVPP TKGTSPTQIW CNNSQLPVDH ILAGSFETAM RLLHDQVGVV QFGPYKQLFL 960
QTYARGRTTY QALPCLPSMY SYPNRNWKDA GLKNGVPAVG LKLNDLIQRL QLCYQLSTVG 1020
KFEDAVEKFR SILLSVPLLV VDNKQEIAEA QQLITICREY IVGLCMEIER KKLPKETLDQ 1080
QKRICEMAAY FTHSNLQPVH MILVLRTALN LFFKLKNFKT AATFARRLLE LGPKPEVAQQ 1140
TRKILSACEK NPTDACQLNY DMHNPFDICA ASYRPIYRGK PVEKCPLSGA CYSPEFKGQI 1200
CRVTTVTEIG KDVIGLRISP LQFR 1224 
Gene Ontology
 GO:0030126; C:COPI vesicle coat; IEA:InterPro.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0030157; P:pancreatic juice secretion; IEA:Compara.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 
Interpro
 IPR016391; Coatomer_asu.
 IPR010714; Coatomer_asu_C.
 IPR006692; Coatomer_WD-assoc_reg.
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF04053; Coatomer_WDAD
 PF06957; COPI_C
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.