CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044371
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 SLC6A9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
20AVPSEATKRDQNLKRubiquitination[1, 2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 579 AA 
Protein Sequence
MVGKGAKGML NGAVPSEATK RDQNLKRGNW GNQIEFVLTS VGYAVGLGNV WRFPYLCYRN 60
GGGAFMFPYF IMLIFCGIPL FFMELSFGQF ASQGCLGVWR ISPMFKGVGY GMMVVSTYIG 120
IYYNVVICIA FYYFFSSMTH VLPWAYCNNP WNTHDCAGVL DASNLTNGSR PAALPSNLSH 180
LLNHSLQRTS PSEEYWRLYV LKLSDDIGNF GEVRLPLLGC LGVSWLVVFL CLIRGVKSSG 240
KVVYFTATFP YVVLTILFVR GVTLEGAFDG IMYYLTPQWD KILEAKVWGD AASQIFYSLG 300
CAWGGLITMA SYNKFHNNCY RDSVIISITN CATSVYAGFV IFSILGFMAN HLGVDVSRVA 360
DHGPGLAFVA YPEALTLLPI SPLWSLLFFF MLILLGLGTQ FCLLETLVTA IVDEVGNEWI 420
LQKKTYVTLG VAVAGFLLGI PLTSQAGIYW LLLMDNYAAS FSLVVISCIM CVAIMYIYGE 480
HSSLRPPATR PLARPLCPAG LLTPHLSRAP ELLPGHPDDA GIPTTPLLSD LLALRLSRHH 540
LPPGSGPPPP PPESSSLRVA PGAERAPPPA PTARGSAGA 579 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
 GO:0005283; F:sodium:amino acid symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR003028; Na/ntran_symport_glycine_GLY1. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR01204; GLY1TRNSPORT.
 PR00176; NANEUSMPORT.