CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011404
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coronin-like protein 
Protein Synonyms/Alias
  
Gene Name
 CRN1 
Gene Synonyms/Alias
 YLR429W; L9576.2 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
572TKSPEQEKSATPPSSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 REPEAT 79 110 WD 1.
 REPEAT 138 169 WD 2.
 REPEAT 180 210 WD 3.
 REPEAT 226 257 WD 4.
 MOD_RES 454 454 Phosphoserine.
 MOD_RES 456 456 Phosphoserine.
 MOD_RES 517 517 Phosphothreonine.
 MOD_RES 529 529 Phosphothreonine.
 MOD_RES 573 573 Phosphoserine.
 MOD_RES 579 579 Phosphoserine.  
Keyword
 Actin-binding; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 651 AA 
Protein Sequence
MSGKFVRASK YRHVFGQAAK KELQYEKLKV TNNAWDSNLL KTNGKFIAVN WNASGGGAFA 60
VIPIEEVGKA PDQVPLFRGH TAQVLDTDFD PFNDHRIASG SDDSKIGIWD IPENYKFHDH 120
VDEDGEPIDI KPVKFLTGHA RKVGHVLYHP VAENVLASSS GDYTVKLWNV ETGKDMITLK 180
HPDMVTSMSF SYDGNYLATV ARDKKLRVWN IREEKIVSEG PAHTGAKNQR VVWLGNSDRL 240
ATTGFSKLSD RQIGIWDAFN IEKGDLGGFY TVDQSSGILM PFYDEGNKIL YLVGKGDGNI 300
RYYEFQNDEL FELSEFQSTE AQRGFAVAPK RMVNVKENEV LKGFKTVVDQ RIEPVSFFVP 360
RRSEEFQEDI YPDAPSNKPA LTAEEWFSGK SVEGPILVSM RSIYDGSAPS FHEAKRPQQP 420
TTQETALEEK KEQPKVEKPI SESEKEVKQE APKSPSPLKS ASSSSTINHV LKEDNSINKL 480
LKKSSDIDQV NNAEDPSRDT SGWEEADDEP APIKIETPVT PTETKKDRTP KVEPSKELKP 540
EPVSIATDRK QEQSLPQEEK SSEKTKSPEQ EKSATPPSSI TAAKTAITAS SKEEPSAART 600
SPKSLGLKKS VEKLSTLVLQ LEDVVDKLTK ANLDKDERLL KLEQKIGELS K 651 
Gene Ontology
 GO:0030479; C:actin cortical patch; IDA:SGD.
 GO:0005826; C:actomyosin contractile ring; IBA:RefGenome.
 GO:0051015; F:actin filament binding; IDA:SGD.
 GO:0008017; F:microtubule binding; IDA:SGD.
 GO:0030674; F:protein binding, bridging; IDA:SGD.
 GO:0051666; P:actin cortical patch localization; IMP:SGD.
 GO:0007015; P:actin filament organization; IMP:SGD.
 GO:0007017; P:microtubule-based process; IPI:SGD.
 GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IMP:SGD.
 GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IDA:SGD. 
Interpro
 IPR015505; Coronin.
 IPR027342; Coronin_fungal.
 IPR015048; DUF1899.
 IPR015049; DUF1900.
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF08953; DUF1899
 PF08954; DUF1900
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.