CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028644
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 26S protease regulatory subunit 6A 
Protein Synonyms/Alias
  
Gene Name
 Psmc3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
19SPVTRQEKMATVWDEacetylation[1]
19SPVTRQEKMATVWDEubiquitination[2]
38GIGEEVLKMSTEEIVubiquitination[2]
86KGKCAVIKTSTRQTYubiquitination[2]
105IGLVDAEKLKPGDLVubiquitination[2]
107LVDAEKLKPGDLVGVubiquitination[2]
134TEYDSRVKAMEVDERubiquitination[2]
170IVLPMNHKEKFENLGubiquitination[2]
172LPMNHKEKFENLGIQacetylation[1]
172LPMNHKEKFENLGIQubiquitination[2]
182NLGIQPPKGVLMYGPubiquitination[2]
194YGPPGTGKTLLARACubiquitination[2]
206RACAAQTKATFLKLAubiquitination[2]
211QTKATFLKLAGPQLVubiquitination[2]
237RDAFALAKEKAPSIIubiquitination[2]
239AFALAKEKAPSIIFIubiquitination[2]
255ELDAIGTKRFDSEKAubiquitination[2]
261TKRFDSEKAGDREVQubiquitination[2]
333IMQIHSRKMNVSPDVubiquitination[2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 400 AA 
Protein Sequence
MQEMNLLPTP ESPVTRQEKM ATVWDEAEQD GIGEEVLKMS TEEIVQRTRL LDSEIKLLDV 60
DPNDQEEDGA NIDLDSQRKG KCAVIKTSTR QTYFLPVIGL VDAEKLKPGD LVGVNKDSYL 120
ILETLPTEYD SRVKAMEVDE RPTEQYSDIG GLDKQIQELV EAIVLPMNHK EKFENLGIQP 180
PKGVLMYGPP GTGKTLLARA CAAQTKATFL KLAGPQLVQM FIGDGAKLVR DAFALAKEKA 240
PSIIFIDELD AIGTKRFDSE KAGDREVQRT MLELLNQLDG FQPNTQVKVI AATNRVDILD 300
PALLRSGRLD RKIEFPMPNE EARARIMQIH SRKMNVSPDV NYEELARCTD DFNGAQCKAV 360
CVEAGMIALR RGATELTHED YMEGILEVQA KKKANLQYYA 400 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0001824; P:blastocyst development; IMP:MGI.
 GO:0030163; P:protein catabolic process; IEA:InterPro. 
Interpro
 IPR005937; 26S_Psome_P45.
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA 
SMART
 SM00382; AAA 
PROSITE
 PS00674; AAA 
PRINTS