CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000618
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Liprin-beta-2 
Protein Synonyms/Alias
 Coiled-coil-like protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF-interacting protein-binding protein 2 
Gene Name
 Ppfibp2 
Gene Synonyms/Alias
 Cclp1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
213EELLQELKHLKIKVEubiquitination[1]
216LQELKHLKIKVEELEacetylation[2]
308ELTGLLNKYLRVKEIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A (By similarity). 
Sequence Annotation
 DOMAIN 564 628 SAM 1.
 DOMAIN 636 699 SAM 2.
 DOMAIN 724 789 SAM 3.
 MOD_RES 328 328 Phosphoserine.
 MOD_RES 384 384 Phosphoserine.
 MOD_RES 518 518 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 882 AA 
Protein Sequence
MTSDASHMLE AALEQMDGII AGTKTAADFS DGTCEPGLSP PSTCLNSMPV LHLIEDLRLA 60
LEMLALPQER EALLSQVPGP TATYIKEWFE DSLSQVNHHG AASNETYQER LARLEGDKES 120
LILQVSVLTD QVEAQGEKIR DLEVCLEGHQ VKLNAAEEML QQELLSRTSL ETQKLDLMTE 180
VSELKLKLVG MEKEQKEQEE KQRKAEELLQ ELKHLKIKVE ELENERNQYE WELKATKAEV 240
AQLQEQVALK DAEIERLHSQ LSRSAALHSD HAERDQEIHR LKMGMETLLV ANEDKDRRIE 300
ELTGLLNKYL RVKEIVMATQ GPSERTLSIN EDEIEGSFRK WNTTNKSPEE VPKQEISPRC 360
SSPTPGPPPL PQKSLESRAQ KKLSCSLEDL RRESGDKCVD GNQLSPVGEP KDSSFLAEQK 420
YPTLPGKLSG ATPNGEAAKS PPTASLQPDS SGSSQPKLRD TEGGWEDIVS SASSGTESSP 480
QSPVTPDGKR SPKGIKKFWG KIRRTQSGNF NTDAPGMAEF RRGGLRATAG PRLSRTRDTK 540
GQKCDANAPF AQWSTERVCT WMEDFGLGQY VIFARQWVTS GHTLLTATPQ DMEKELGIKH 600
PLHRKKLVLA VKAINAKQEE TSALLDHIWV TRWLDDIGLP QYKDQFHESR VDGRMLQYLT 660
VNDLLFLKVT SQLHHLSIKC AIHVLHVNKF NPNCLHRRPA DESNLSPSEV VQWSNHRVME 720
WLRSVDLAEY APNLRGSGVH GGLIILEPRF TGDTLAMLLN IPPQKTLLRR HLTTKFNALI 780
GPEAEQEKRD KMASPAYTPL TTTAKVRPRK LGFSHFGNMR KKKFDESTDY ICPMEPGDAV 840
SDSHRVYGVY RGLSPLDNHE LDGLDQMAPS EGTVTQIGLL SQDIHRLTTL LSQDQLLNDP 900
PGCP 904 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008907; F:integrase activity; IEA:InterPro. 
Interpro
 IPR004191; Integrase_Tn916-type_DNA-bd_N.
 IPR001660; SAM.
 IPR013761; SAM/pointed.
 IPR011510; SAM_2.
 IPR021129; SAM_type1. 
Pfam
 PF02920; Integrase_DNA
 PF00536; SAM_1
 PF07647; SAM_2 
SMART
 SM00454; SAM 
PROSITE
 PS50105; SAM_DOMAIN 
PRINTS