UniProt Accession

 CF089_HUMAN; Q6UWU4; B4DTT1; F4NAR0; F4NAR1; Q6ZMG5; Q7Z356; Q8IZ35 

Genbank Protein ID

 FR832871; FR832872; AY358637; AK172780; AK300351; BX538108; AL122034; AL122034; CH471081; BC023605; BC095423; BC105947; BC107489; BC105946 

Genbank Nucleotide ID

 CCA30148.1; CCA30149.1; AAQ89000.1; BAD18761.1; BAG62093.1; CAD98021.1; CAI23297.1; CAI23299.1; EAX03920.1; AAH23605.2; AAH95423.1; AAI05948.1; AAI07490.1; AAI05947.1 

Protein Name

 Bombesin receptor-activated protein C6orf89 

Protein Synonyms/Alias

 Amfion 

Gene Name

 C6orf89 

Gene Synonyms/Alias

 BRAP; UNQ177/PRO203 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
40	HQCGMSEKAIEKFIR	ubiquitination	[1]
44	MSEKAIEKFIRQLLE	ubiquitination	[1, 2]
263	FTHLPFPKDASLNKC	ubiquitination	[1]
269	PKDASLNKCSFLHPE	ubiquitination	[1]
282	PEPVVGSKMHKMPDL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Exhibits histone deacetylase (HDAC) enhancer properties. May play a role in cell cycle progression and wound repair of bronchial epithelial cells. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Golgi apparatus; Membrane; Nucleus; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 347 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IDA:UniProtKB.
 GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.
 GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
 GO:0042060; P:wound healing; IDA:UniProtKB. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS