UniProt Accession

 H0YLW0_HUMAN; H0YLW0 

Genbank Protein ID

 AC025168 

Genbank Nucleotide ID

  

Protein Name

 Signal recognition particle 14 kDa protein 

Protein Synonyms/Alias

  

Gene Name

 SRP14 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
27	KNKTKKTKAAAAAAA	methylation	[1, 2]
27	KNKTKKTKAAAAAAA	ubiquitination	[3, 4]

Reference

 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [2] Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome.
 Bremang M, Cuomo A, Agresta AM, Stugiewicz M, Spadotto V, Bonaldi T.
 Mol Biosyst. 2013 Jul 30;9(9):2231-47. [PMID: 23748837]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 56 AA 

Protein Sequence

Gene Ontology

 GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:InterPro.
 GO:0008312; F:7S RNA binding; IEA:InterPro.
 GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
 GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro. 

Interpro

 IPR003210; Signal_recog_particle_SRP14.
 IPR009018; Signal_recog_particle_SRP9/14. 

Pfam

  

SMART

  

PROSITE

  

PRINTS